Table 1.
Diagnosis of Eosinophilic Esophagitis (EoE) and Eosinophilic Gastroenteritis (EGE).
| EoE | EGE | |
|---|---|---|
| Age | 30-50 years | All ages |
| Male/female ratio | 4:1 | 1:1 |
| Symptoms | Dysphagia | Abdominal pain |
| Heartburn | Nausea/vomiting | |
| Diarrhea | ||
| Laboratory tests | Eosinophilia 30% | Eosinophilia 80% |
| Elevated TARC | ||
| Endoscopy | Characteristics | Non-specific |
| longitudinal furrows | normal >60% | |
| white plaque | edema | |
| rings | redness | |
| others | erosion/ulcer | |
| CT | Rare | Frequent |
| thickened esophageal wall | segmental thickening of gut ascites | |
| Histology | Eosinophils >15/HPF Basal zone hyperplasia Dilated intracellular space Papilla elongation |
No consensus regarding eosinophil density Intraepithelial eosinophils Villous atrophy |
| Surface layering of eosinophils Eosinophilic microabscess Mast cell infiltration |
Crypt hyperplasia Eosinophilic abscess Mast cell infiltration |
|
| Others | Others |