Table 13.
COR* | LOE* | Genetic Variant | Risk Factors | Aortic Diameter (cm) |
---|---|---|---|---|
2a | C-LD | ACTA2 | No | ≥4.5 |
2b | C-EO | ACTA2 | Yes† | ≥4.2 |
2b | C-LD | PRKG1 | No | ≥4.2 |
2b | C-EO | PRKG1 | Yes† | ≥4.0† |
Patient has risk factors for aortic dissection (family history of type A aortic dissection with minimal aortic enlargement, aortic growth rate ≥0.3 cm/y) or significant valve disease requiring surgery.
Earlier surgery may be considered in patients with a family history of type A aortic dissection in the setting of no or minimal aortic dilation, aortic growth rate ≥0.3 cm/y, or at the patient’s request.
Colors correspond to COR and LOE in Table 2.
COR indicates class of recommendation; and LOE, level of evidence.