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. Author manuscript; available in PMC: 2023 Dec 13.
Published in final edited form as: Circulation. 2022 Nov 2;146(24):e334–e482. doi: 10.1161/CIR.0000000000001106

Table 8.

Risk Factors for Familial TAD

TAD and syndromic features of Marfan syndrome, Loeys-Dietz syndrome, or vascular Ehlers-Danlos syndrome
TAD presenting at age <60 y
A family history of either TAD or peripheral/intracranial aneurysms in a first- or second-degree relative
A history of unexplained sudden death at a relatively young age in a first- or second-degree relative

TAD indicates thoracic aortic disease.