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. 2022;15(4):343–359. doi: 10.22037/ghfbb.v15i4.2496

Table 1.

The main types of serological test used in the diagnosis of amoebiasis

Test Intestinal amoebiasis
Specificity / Sensitivity
Extra-intestinal amoebiasis
Specificity / Sensitivity
References
Bentonite flocculation (BF) 100% 86% 100% 93% 93
Cellulose acetate membrane precipitation (CAP) 100% 90.9% 100% 87.7-97.5% 95, 104
Counter immune electrophoresis (CIEP) 98.2% 18-96% 98.2% 84-100% 94,103
Enzyme linked immunosorbent assay (ELISA) 97-100% 70-92% 94.8-100% 80-100% 71, 72, 73, 74, 99
Fluorescent immunoassay (FIA) 100% 92.1% 100% 92.1% 102
Immuno electrophoresis (IE) Unknown 66,7 100 96.8-100% 95
Indirect immunofluorescence assay (IFA) 100% 60- 95% 96.7-98% 93.6-100% 34-80, 98, 100
Indirect haemagglutination (IHA) 96.77-99.1% 75-96.77% 88.7-99.8% 62-99% 76, 77, 78, 30, 35, 92, 97
Latex agglutination (LA) 81.8-98.11% 75-96% 92.5-99.5% 93 -98% 35, 96, 31, 97
Gel diffusion precipitin test (GDP) 99.1% 60-85% 100% 95-97.1% 32, 101