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. 2022 Apr 22;93(1):207–216. doi: 10.1038/s41390-022-02052-5

Table 3.

Treatments received stratified by comorbidity (patients with asymptomatic or incidental SARS-CoV-2 infections excluded).

Total N No/Unknown comorbidity Comorbidity present p
Total N (%) 938 (58.0) 679 (42.0)
Antibiotic medication 1477 (91.3) No 301 (32.1) 216 (31.8) 0.273
Yes 529 (56.4) 431 (63.5)
(Missing) 108 (11.5) 32 (4.7)
Antiviral 1476 (91.3) No 787 (83.9) 595 (87.6) 0.027
Yes 42 (4.5) 52 (7.7)
(Missing) 109 (11.6) 32 (4.7)
Maximal steroid therapy 1422 (87.9) None 713 (76.0) 475 (70.0) <0.001
Oral 53 (5.7) 103 (15.2)
IV 42 (4.5) 36 (5.3)
(Missing) 130 (13.9) 65 (9.6)
Maximum respiratory support 1550 (95.9) No respiratory support 738 (78.7) 427 (62.9) <0.001
Supplemental oxygen 59 (6.3) 108 (15.9)
High flow support 21 (2.2) 47 (6.9)
Non-invasive 25 (2.7) 35 (5.2)
Invasive 33 (3.5) 57 (8.4)
(Missing) 62 (6.6) 5 (0.7)
ICU/HDU admission 1548 (95.7) No 764 (81.4) 536 (78.9) <0.001
Yes 112 (11.9) 136 (20.0)
(Missing) 62 (6.6) 7 (1.0)
Inotrope 1451 (89.7) No 764 (81.4) 612 (90.1) 0.274
Yes 47 (5.0) 28 (4.1)
(Missing) 127 (13.5) 39 (5.7)
Total PEWS 1518 (93.9) Median (IQR) 2.0 (1.0–4.0) 2.0 (1.0–5.0) 0.014
PEWS over 2 1518 (93.9) No 471 (50.2) 351 (51.7) 0.315
Yes 380 (40.5) 316 (46.5)
(Missing) 87 (9.3) 12 (1.8)
Length of stay 1368 (84.6) Median (IQR) 2.0 (1.0–3.0) 3.0 (1.0–7.0) <0.001

ICU intensive care unit, HDU high dependency unit, PEWS Paediatric Early Warning Score at presentation.