Table 2.
Visual oral ulcerative mucositis score118: based on a modification of the method of Sonis et al.119.
| Grade | Severity | Description |
|---|---|---|
| 0 | Normal (no abnormalities) | |
| 1 | Mild | Partial hyperemia, erythema and swelling, with no evidence of mucosal erosion (mucosa intact) |
| 2 | Mild | Overall hyperemia, erythema and swelling and superficial erosion, may include mild sloughing |
| 3 | Moderate | Epidermolysis, hyperemia and erythema; moderate mucositis characterized by frank ulcer formation. Ulcers typically have areas of necrosis (erosion) with associated yellowish/grey coloration with pseudomembrane formation |
| Cumulative area of ulceration ≤ 25% of tongue surface area | ||
| 4 | Severe | Extensive epidermolysis and bleeding; severe mucositis with ulcer formation affecting 25–50% of tongue or buccal mucosal area. Marked erythema and pseudomembrane formation. Loss of pliability |
| 5 | Severe | Bleeding and abscesses; virtually complete ulceration of the mucosa, all mucosa areas at risk. Loss of mobility and pliability |