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. 2001 Oct;69(10):6364–6369. doi: 10.1128/IAI.69.10.6364-6369.2001

TABLE 1.

Cytokine level in BAL fluid of K. pneumoniae-infected and uninfected (day 0) micea

Day Type of mice Concn (pg/ml) of
MCP-1 IL-12 IFN-γ TNF-α IL-10
0 CCL3+/+ <18 <12 73 ± 5 97 ± 14 60 ± 6
CCL3−/− <18 <12 59 ± 5 76 ± 6 42 ± 12
1 CCL3+/+ 22 ± 9 15 ± 10 82 ± 31 98 ± 30 38 ± 10
CCL3−/− 49 ± 20 73 ± 54 34 ± 11 82 ± 23 19 ± 10
2 CCL3+/+ 311 ± 131* 192 ± 79 375 ± 211* 219 ± 76* 66 ± 23
CCL3−/− 649 ± 159* 281 ± 205* 508 ± 320* 785 ± 297* 47 ± 19
3 CCL3+/+ 201 ± 120* 1,166 ± 838* 784 ± 497* 386 ± 239* 34 ± 14
CCL3−/− 405 ± 106* 900 ± 663* 1,193 ± 597* 512 ± 278* 25 ± 15
a

Cytokine level in BAL fluid of K. pneumoniae-infected CCL3+/+ and CCL3−/− mice (n = 5 to 7 per time point, from two independent experiments). *, P < 0.05, compared to day 0. Infected CCL3−/− animals did not differ significantly from infected CCL3+/+ animals at any time point.