Table 5.

Intervention and time effects on diabetes risk and metabolic mortality vulnerability makers.

	LSMEAN (95% CI)			p value
	Baseline	6 Month	12 Month	Group	Time	Group × Time
n
DIET	124	107	89	-	-	-
DIET+PA150	127	105	88	-	-	-
DIET+PA250	123	107	86	-	-	-
GlycA, μmol/L				0.777	<0.0001***	0.009**
DIET	414.8 (402.8, 426.8)	392.6 (380.3, 404.9)	370.0 (357.3, 382.6)
DIET+PA150	411.3 (399.4, 423.2)	394.7 (382.4, 407.0)	378.3 (365.5, 391.1)
DIET+PA250	418.4 (406.5, 430.4)	388.1 (375.6, 400.5)	386.2 (373.4, 399.1)
LP-IR, score 0–100				0.934	<0.0001***	0.919
DIET	45.3 (41.3, 49.4)	34.9 (30.7, 39.0)	33.5 (29.2, 37.8)
DIET+PA150	47.1 (43.1, 51.1)	34.8 (30.6, 38.9)	34.3 (29.9, 38.6)
DIET+PA250	46.8 (42.8, 50.8)	34.5 (30.3, 38.7)	34.5 (30.2, 38.9)
DRI, score 0–100				0.921	<0.0001***	0.989
DIET	48.0 (45.2, 50.8)	40.8 (37.8, 43.7)	39.9 (36.8, 42.9)
DIET+PA150	47.9 (45.1, 50.7)	40.4 (37.5, 43.3)	39.7 (36.6, 42.8)
DIET+PA250	47.8 (45.0, 50.6)	39.6 (36.6, 42.5)	39.4 (36.3, 42.5)

Values are least square mean (95% confidence interval); LP-IR = Lipoprotein Insulin Resistance Index; DRI = Diabetes Risk Index; All analyses were adjusted for sex and race (white/non-white).

^*p<0.05;

^**p<0.01;

^***p<0.0001