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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2022 Dec 29;43(2):234–252. doi: 10.1161/ATVBAHA.122.318135

Figure 4. Chromatin accessibility landscape and TEAD motif distribution at the locus of Lox and other adaptive genes in smooth muscle cell (SMC) clusters.

Figure 4.

A, Accessibility and peaks detected at the chromatin regions of 8 selected adaptive genes. Accessibility was shown for SMCs under different conditions. Peaks harboring TEAD motifs were highlighted in red. B, Aortic stress–inducible peaks at the Lox gene locus and the distal peaks that were co-accessible with peaks at the Lox gene locus in SMC clusters are shown. The distribution of TEAD motifs on aortic stress–inducible Lox peaks in SMC clusters is shown.