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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Nat Biomed Eng. 2022 Dec 23;7(1):72–84. doi: 10.1038/s41551-022-00973-4

Extended Data Fig. 3 |. Cellular uptake of Mann-NC among tumor cells and innate immune cells in local tumors.

Extended Data Fig. 3 |

BALB/c mice were inoculated subcutaneously with 1.5 × 105 CT26 cells on day 0 and treated by intratumoral administration of Cy5.5-Mann-NC on day 9. After 3 days, tumor tissues were analysed for Cy5.5+ cells among CD45- tumor cells, CD11c + DCs, Ly6C+ monocytes, F4/80+ macrophages, and Ly6G+ neutrophils. Data represent mean ± SEM, from a representative experiment with n = 5 biologically independent samples from two independent experiments.