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. 2023 Jan 12;13:1044798. doi: 10.3389/fphar.2022.1044798

TABLE 3.

Logistic regression analysis of the associated factors of biosimilar uptake (n = 446).

Variables Model 1 Model 2 Model 3
OR (95%CI) p-value OR (95%CI) p-value Β (95%CI) p-value
Patient’s age 1.04(1.01–1.07) <0.01 1.03(1.01–1.06) 0.02 .12(.04–.20) <0.01
Tumor stage (Ref. I ∼ II)
 III .85(.42–1.71) 0.64 .87(.42–1.81) 0.71 −.14(-.87–.59) 0.72
 IV 1.73(.95–3.14) 0.07 1.78(.95–3.34) 0.07 .55(-.09–1.18) 0.09
Type of health insurance coverage (Ref. urban employee program)
 urban and rural resident program 1.93(1.11–3.33) 0.02 1.87(1.06–3.29) 0.03 .67(.10–1.24) 0.02
 others 1.74(.16–18.7) 0.65 2.18(.17–28.3) 0.56 1.06(-1.53–3.65) .42
Whether treatment with trastuzumab was initiated before January 2021 (Ref. no)
 yes .41(.16–1.03) 0.06 .36(.14–.95) 0.04 −1.04(-2.00∼-.09) 0.03
Physician’s age .91(.86–.97) <0.01 −.09(-.15∼-.04) <0.01
Physician’s gender (Ref. male)
 female 2.30(1.31–4.02) <0.01 .84(.28–1.40) <0.01
Physician’s academic rank (Ref. deputy chief physician)
 chief physician 4.35(2.01–9.39) <0.01 1.73(.85–2.61) <0.01
The interaction term of patients’ age and physicians’ academic rank −.10(-.19∼-.01) 0.03