Table 1.
Physicochemical Properties and Classification of Endothelium-Derived Factors
| Factor | Property | Classification |
|---|---|---|
| NO | Inorganic gases | EDRF |
| PGI2 | Arachidonic acid metabolites | EDRF |
| H2S | Inorganic gases | EDRF, EDHF |
| K+ | Ion | EDRF, EDHF |
| EETs | Arachidonic acid metabolites | EDRF, EDHF |
| Ang-(1-7) | Bioactive peptide | EDRF |
| Adenosine | Nucleoside | EDRF |
| EC-derived ATP | Nucleotide | EDRF |
| ROS | Oxygen radical | EDCF |
| EC-derived ADP | Nucleotide | EDCF |
| EC-derived Up4A | Nucleotide | EDCF |
| ET-1 | Bioactive peptide | EDCF |
| 5-HT | Small organic molecule | EDCF |
| TXA2 | Arachidonic acid metabolites | EDCF |
| 8-iso-PGF2α | Arachidonic acid metabolites | EDCF |
| Ang II | Bioactive peptide | EDCF |
5-HT = 5-hydroxytryptamine; Ang = angiotensin; EC = endothelial cell; EDCF = endothelium-derived contracting factor; EDHF = endothelium-derived hyperpolarizing factor; EDRF = endothelium-derived relaxing factor; EET = epoxyeicosatrienoic acid; ET-1 = endothelin 1; PG = prostaglandin; ROS = reactive oxygen species; TXA2 = thromboxane A2; Up4A = uridine adenosine tetraphosphate.