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. 2023 Jan 26;49:15. doi: 10.1186/s13052-023-01418-7

Table 2.

Recommendations for the pharmacological management of IBD after the peak of the COVID-19 pandemic (adapted from the SIGENP position paper) [16]

Topic Recommended
Steroids for induction Yes (accelerated steroid weaning if clinically indicated)
Suspension of immunomodulators
 ▪As monotherapy No
 ▪As combination therapy No
Suspension of biologics
 ▪As monotherapy No
 ▪As combination therapy No
 Start of immunosuppressants or anti-TNF-α Yes
 Intervals and doses of anti-TNF-α Regular
 RT-PCR/serological screening for SARS-CoV-2 before starting anti-TNF-α therapy No
 Vedolizumab and ustekinumab use Yes (not contraindicated)

TNF-α, tumor necrosis factor-α; RT-PCR, real time-polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2