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. 2023 Jan 10:10.1111/1440-1681.13744. Online ahead of print. doi: 10.1111/1440-1681.13744

FIGURE 1.

FIGURE 1

The proposed mechanism model responsible for curcumin's protective effects in mice following LPS/KP. Cyclodextrin‐complexed curcumin (CDC) inhibits the production of proinflammatory cytokines by targeting the NF‐κB pathway. CDC targets NF‐κB signalling by inhibiting the activation of IL‐1β, IL‐6 and MCP1. KP, Klebsiella pneumoniae; CDC,; NF‐κB, nuclear factor‐κB; IL, interleukin; MCP1, monocyte chemoattractant protein‐1