Table 5.
SARS‐CoV‐2 (sub)varianta | Rho value [95% CI] (p value) for the correlation between the Roche/DiaSorin immunoassays and NtAb titers | ||
---|---|---|---|
All participants | SARS‐CoV‐2 ‐naïve | SARS‐CoV‐2‐experienced | |
Wuhan‐Hu‐1 | 0.69 [0.58−0.77] (<0.001)/0.71 [0.61−0.79] (<0.001) | 0.71 [0.60−0.81] (<0.001)/0.75 [0.64−0.83](<0.001) | 0.40 [0.09−0.64] (<0.001)/0.37 [0.06−0.62] (<0.001) |
Omicron BA.1 | 0.64 [0.52−0.73] (<0.001)/0.67 [0.55−0.75](<0.001) | 0.61 [0.46−0.73] (<0.001)/0.60 [0.45−0.73] (<0.001) | 0.52 [0.24−0.72] (<0.001)/0.59 [0.33−0.77] (<0.001) |
Omicron BA.2 | 0.30 [0.08−0.49] (<0.001)/0.24 [0.02−0.44] (<0.001) | 0.52 [0.27−0.70] (<0.001)/0.49 [0.02−0.68] (<0.001) | −0.05 [(−0.34 to 0.31] (0.78)/−0.15 [−0.48 to 0.21] (0.4) |
Abbreviation: NtAb, neutralizing antibodies.
A total of 127 were assayed for quantitation of NtAb against Wuhan‐Hu‐1 and Omicron BA.1. A total of 83 sera were assayed for NtAb against Omicron BA.2.