Table 1.
Patient ID | Disease group | Age (years) | Spike+ B cells sequenced | RBD+ B cells sequenced | Gender | Days post symptom onset | Spike+ Bcell frequency (/105 B cells) | RBD+ Bcell frequency (/105 B cells) | |||
---|---|---|---|---|---|---|---|---|---|---|---|
t1 | t2 | t1 | t2 | t1 | t2 | ||||||
2850955 | Uninfected control | 26 | n/a | n/a | Male | ||||||
2584766 | Uninfected control | 44 | n/a | n/a | Female | ||||||
250011 a | Mild | 63 | 105 | 76 | Female | 68 | 181 | 224 | 41 | 47 | 71 |
250017 b | Mild | 78 | 105 | Male | 73 | 138 | 60 | 85 | 71 | 175 | |
213021 f | Mild | 52 | 51 | Male | 81 | 147 | 28.2 | 62 | 7.1 | 33 | |
213007 g | Moderate | 34 | 0 | 146 | Male | 67 | 132 | 202 | 133 | 418 | 44 |
289036 c | Severe | 84 | 0 | 133 | Female | 87 | 156 | 53 | 67 | 142 | 138 |
247004 d | Severe | 23 | 0 | 143 | Male | 58 | 116 | 155 | 106 | 329 | 355 |
250002 e | Severe | 72 | 43 | 121 | Male | 49 | 110 | 40 | 48 | 38 | 64 |
BD, two times a day; n/a, not available; PRN, pro re nata (as needed); QID, four times a day; RBD, receptor‐binding domain.
Had obesity and no treatments. SpO2 of 98%.
Had hypertension and was a smoker. SpO2 not calculated.
Telmisartan 80 mg mane; amlodipine 5 mg mane; sitagliptin 100 mg mane; allopurinol 1 tablet every 2 days; Movicol 2 sachets BD PRN for constipation; paracetamol 1 g QID PRN for fever. Had hypertension, diabetes and obesity. Optimal oxygen saturation (SpO2) of 71.7%.
Penrindopril, amlondopril, clotrimazole, prednisone, benzylpenicillin–ceftriaxone–doxycycline, rosuvastatin. Chronic lung disease (asthma). Smoker. SpO2 of 92%.
Ibuprofen prior to admission. Inpatient: paracetamol, nebulized saline. SpO2 of 91%.
No comorbidity or documented treatment. SpO2 not calculated.
SpO2 of 99%.