Skip to main content
. 2022 Dec 1:10.1111/imcb.12607. Online ahead of print. doi: 10.1111/imcb.12607

Table 1.

Characteristics of the study population and infection severity

Patient ID Disease group Age (years) Spike+ B cells sequenced RBD+ B cells sequenced Gender Days post symptom onset Spike+ Bcell frequency (/105 B cells) RBD+ Bcell frequency (/105 B cells)
t1 t2 t1 t2 t1 t2
2850955 Uninfected control 26 n/a n/a Male
2584766 Uninfected control 44 n/a n/a Female
250011 a Mild 63 105 76 Female 68 181 224 41 47 71
250017 b Mild 78 105 Male 73 138 60 85 71 175
213021 f Mild 52 51 Male 81 147 28.2 62 7.1 33
213007 g Moderate 34 0 146 Male 67 132 202 133 418 44
289036 c Severe 84 0 133 Female 87 156 53 67 142 138
247004 d Severe 23 0 143 Male 58 116 155 106 329 355
250002 e Severe 72 43 121 Male 49 110 40 48 38 64

BD, two times a day; n/a, not available; PRN, pro re nata (as needed); QID, four times a day; RBD, receptor‐binding domain.

a

Had obesity and no treatments. SpO2 of 98%.

b

Had hypertension and was a smoker. SpO2 not calculated.

c

Telmisartan 80 mg mane; amlodipine 5 mg mane; sitagliptin 100 mg mane; allopurinol 1 tablet every 2 days; Movicol 2 sachets BD PRN for constipation; paracetamol 1 g QID PRN for fever. Had hypertension, diabetes and obesity. Optimal oxygen saturation (SpO2) of 71.7%.

d

Penrindopril, amlondopril, clotrimazole, prednisone, benzylpenicillin–ceftriaxone–doxycycline, rosuvastatin. Chronic lung disease (asthma). Smoker. SpO2 of 92%.

e

Ibuprofen prior to admission. Inpatient: paracetamol, nebulized saline. SpO2 of 91%.

f

No comorbidity or documented treatment. SpO2 not calculated.

g

SpO2 of 99%.