Table 1.
Baseline characteristics of patients with AIIRDs and healthy controls
| Characteristics | COVID‐19 vaccination | ||
|---|---|---|---|
| AIIRDs patients | Healthy controls | p Value | |
| No. of cases | 318 | 318 | NA |
| Gender, n (%) | |||
| Male | 77 (24.2) | 98 (30.8) | 0.062 |
| Female | 241 (75.8) | 220 (69.2) | 0.062 |
| Age, years, median (IQR) | 43 (32−52) | 41 (32−52) | 0.072 |
| Age group in years, n (%) | |||
| 18−30 | 63 (19.8) | 67 (21.1) | 0.694 |
| 31–59 | 223 (70.1) | 227 (71.4) | 0.727 |
| ≥60 | 32 (10.1) | 24 (7.5) | 0.263 |
| BMI (Kg/m2), median (IQR) | 21.9 (19.9–24.0) | 22.0 (20.2−23.9) | 0.407 |
| Medical history, n (%) | 60 (18.9) | 28 (8.8) | <0.001 |
| Hypertension | 24 (7.5) | 12 (3.8) | 0.039 |
| Coronary heart disease | 4 (1.3) | 4 (1.3) | 1.000 |
| Cerebrovascular disease | 2 (0.6) | 1 (0.3) | 1.000 |
| Diabetes mellitus | 10 (3.1) | 5 (1.6) | 0.191 |
| Chronic pulmonary disease | 3 (0.9) | 2 (0.6) | 1.000 |
| Chronic renal disease | 3 (0.9) | 1 (0.3) | 0.624 |
| Chronic liver disease | 11 (3.5) | 1 (0.3) | 0.004 |
| Thyroid disease | 10 (3.1) | 3 (0.9) | 0.050 |
| Chronic infection | 11 (3.5) | 1 (0.3) | 0.004 |
Note: Statistical significance was determined by Mann−Whitney U test and Chi‐square (χ2) test.
Abbreviations: AIIRDs, autoimmune inflammatory rheumatic diseases; BMI, body mass index; IQR, interquartile range; NA, not available.