Table 1.
Summary of respiratory outcomes of infants with severe BPD who received chronic ventilation at home through a tracheostomy.
| Authors, year of publication | Patient Population | Primary Indication for Tracheostomy | Age at Tracheostomy | Rate (%) and Age at liberation from home ventilator | Rate (%) and Age at decannulation | Survival rate (%) after hospital discharge | Follow-up period |
|---|---|---|---|---|---|---|---|
| Cristea et al., 2013 | Preterm infants born at 26 weeks ** (IQR 25, 27) (n = 102) | Severe BPD | Not reported | 97.1% 24 months**(IQR-19–33) |
58.8% 37.5 months** (IQR-31.5–45) |
81.4% | Up to 5–6 years of age (total of 871 person years) |
| Akangire et al., 2020 | Ventilator-dependent infants (n = 204) BPD only (n = 82)# |
Severe BPD Airway Cardiac Neurologic Genetic |
4.9 months* (SD 4.6) | 100% 27.2 months*(SD 23) |
50% 41.9 months*(SD 23.3) |
80.5% | Up to 4 years of age |
| House et al., 2021 | Preterm infants born at < 33 weeks (n = 49) | Severe BPD | 43.3 weeks* (range 36.3-56.9) | 97.0% 27.3 months* (SD 4.1, range 7–45 months) |
79% 44.7 months* (range- 22–79) |
73.9% | Up to 5 years of age |
| Sillers et al., 2021 | Tracheostomy-dependent infants (n = 323) CLD/BPD only (n = 180)# |
Pulmonary Anatomic Cardiac Neurologic Musculoskeletal Other |
52.3 weeks PMA** (IQR 44.3, 60.0) | Not reported | 51.3% 3.1 years** (IQR 2.4, 4.5) |
82% | Minimum of 3 years after tracheostomy placement |
| Akangire et al., 2022 | Tracheostomy dependent infants (n = 98) | Severe BPD | 43 weeks PMA or 4 months**
(IQR 3, 5) |
100%, 24 months** (IQR 18, 29) | 52%, 32 months** (IQR 26, 39) | 99% | Up to 4 years of age |
*Mean.
**
Median.
#
Outcomes for CLD/BPD subgroup only.