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. 2023 Jan 26;13:1460. doi: 10.1038/s41598-023-28797-5

Table 1.

Demographics and clinical characteristics of patients with COVID-19.

Total (n = 280) Mild group (n = 70) Moderate group (n = 70) Severe group (n = 70) Critical group (n = 70) p value*
Age (mean ± SE) 55.1 ± 1.6 58.5 ± 1.3 63.5 ± 1.5 69.2 ± 1.3 0.001
Sex
 Female 120 (42.8%) 45 (64.3%) 30 (42.8%) 25 (35.7%) 20 (28.6%) 0.041
 Male 160 (57.1%) 25 (35.7%) 40 (57.1%) 45 (64.3%) 50 (71.4%) 0.041
Clinical manifestations
 Fever 230 (82.1%) 42 (60%) 55 (78.5%) 63 (90%) 70 (100%) 0.028
 Dry cough 220 (78.6%) 49 (70%) 52 (74.2%) 56 (80%) 63 (90%) 0.138
 Fatigue 216 (77.1%) 41 (58.6%) 50 (71.4%) 59 (84.2%) 66 (94.2%) 0.019
 Dyspnea 160(57.1%) 8 (11.4%) 22 (31.4%) 60 (85.76%) 70 (100%) 0.001
 Myalgia 159 (56.8%) 28 (40%) 36 (51.4%) 45 (64.3%) 50 (71.4%) 0.017
Headache 95 (33.9%) 18 (25.7%) 21 (30%) 25 (35.7%) 31 (44.3%) 0.847
 Nausea and vomitung 91 (31.5%) 36 (51.4%) 27 (38.6%) 17 (24.3%) 11 (15.7%) 0.117
 Anosmia 82 (29.3%) 28 (40%) 19 (27.1%) 10 (14.3%) 6 (8.6%) 0.795
 Chest pain 68 (24.3%) 1 (1.4%) 7 (10%) 18 (25.7%) 42 (60%) 0.004
 Pharyngalgia 28 (13.6%) 13 (18.6%) 11 (15.6%) 9 (12.8%) 5 (7.1%) 0.124
Ausculattory findings
 Normal 38 (13.6%) 29 (41.4%) 9 (12.6%) 0 (0%) 0 (0%) 0.000
 Attenuated breathing sound 150 (53.6%) 28 (40%) 29 (41.4%) 31 (44.3%) 62 (88.6%) 0.044
 Sharpened respiratory sound 92 (32.9%) 13 (45.7%) 32(32.9%) 39 (41.4%) 8 (11.4%) 0.206
 Audible cracks diffusely 152 (54.3%) 6 (8.6%) 35(50%) 47 (67.1%) 64 (91.4%) 0.005
 Audible whistling 90 (32.1%) 4 (5.7%) 17 (2.8%) 27 (21.4%) 42 (37.1%) 0.067
CXR findings
 Normal finding 56 (20%) 56 (80%) 0 (0%) 0 (0%) 0 (0%) 0.001
 Interstitial thickening 56 (20%) 14 (20%) 42 (60%) 0 (0%) 0 (0%) 0.001
 Focal consolidation 28 (10%) 0 (0%) 28 (40%) 0 (0%) 0 (0%) 0.001
 Multifocal consolidation 70 (25%) 0 (0%) 0 (0%) 70 (100%) 0 (0%) 0.001
 Diffuse alveolar changes—ARDS 70 (25%) 0 (0%) 0 (0%) 0 (0%) 70 (100%) 0.001
Length of hospital stay (in days) 7 12 18 28 0.154

Significant values are in italics.

Data expressed as mean, standard error (SR), frequency (percentage).

*p values indicate differences between mild, moderate and severe group p < 0.05 was considered statistically significant.