Table 1.
Subject characteristics of women and their offspring included in the study.
| CTR (n=22) |
EO-PE (n=8) |
LO-PE (n=6) |
|
|---|---|---|---|
| Age | 29.4 ± 3.5 | 34.4 ± 3.6 ** | 34.4 ± 4.0 † |
| BMI before pregnancy (kg/m2) | 22.5 ± 2.9 | 21.0 ± 2.1 | 23.4 ± 3.2 |
| Week of gestation | 38.7 ± 1.5 | 34.2 ± 1.1 **** | 37.7 ± 1.1 |
| Mode of the delivery | SP 10/CS 12 | CS 8 | SP 3/CS 3 |
| Fetal sex | 8♀ 14♂ | 4♀, 4♂ | 2♀, 4♂ |
| Umbilical cord blood Arterial, pH |
7.30 ± 0.06 | 7.31 ± 0.03 | 7.25 ± 0.09 |
| Umbilical cord blood Venous, pH |
7.37 ± 0.06 | 7.36 ± 0.02 | 7.34 ± 0.05 |
| Placental weight (g) | 616.7 ± 123.0 | 425.7 ± 63.7 | 506.7 ± 82.8 |
| Birth weight (g) | 3345 ± 398 | 1996 ± 404.7 **** | 2955 ± 288.9 |
| Birth weight percentile | 49.2 ± 21.2 | 24.0 ± 18.7 ** | 34.3 ± 11.3 |
| Systolic blood pressure (mmHg) | 115.1 ± 6.9 | 162 ± 12.1**** | 153.2 ± 20.9 †††† |
| Diastolic blood pressure (mmHg) | 72.9 ± 10.2 | 94.3 ± 8*** | 103 ± 13.3 †††† |
| sFlt-1 [pg/mL] | / | 14472 ± 5083 ‡ | 8257 ± 2881 |
| PlGF [pg/mL] | / | 66.2 ± 24.3 | 81.6 ± 13.02 |
| sFlt-1/PlGF [pg/mL] | / | 248.7 ± 118.1 | 105.5 ± 51.9 |
| Platelets [109/L] | 218.3 ± 63.1 | 221.9 ± 106.3 | 191.8 ± 60.8 |
| Uric acid [mg/dL] | / | 6.3 ± 1.4 | 5.9 ± 0.7 |
| AST [U/L] | / | 21.0 ± 6.3 | 21.2 ± 4.2 |
| ALT [U/L] | / | 17.4± 5.6 | 12.7 ± 4.8 |
BMI, body-mass index; SP, spontaneous delivery; CS, caesarean section; All data are shown as mean ± SD. Statistical significance was assessed by one-way ANOVA with Tukey’s post-hoc test. If normality testing failed, Kruskal-Wallis test with Dunn’s post-hoc test was used. When comparing two groups’ Students t-test was used. **p ≤ 0.01, ***p ≤ 0.001 and ****p ≤ 0.0001; whereas *CTR vs EO-PE. †p ≤ 0.05 and † † † †p ≤ 0.0001; whereas †CTR vs LO-PE. ‡ represents comparison between EO-PE vs LO-PE; whereas ‡ p ≤ 0.05.