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Alignment of epitope phage sequence with botulinum toxin and binding domain (HC) protein sequences. The DNA sequence of inserts from ELISA-positive clones was determined and aligned against the BoNT/A HC sequence using BLAST. The corresponding residues of each individual clone are indicated at the N and C termini. The sequences of the S25 and 3D12 clones overlap the C-terminal binding domain, while the C25 sequence overlaps the entire binding domain.
