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. 2023 Jan 12;13:1025346. doi: 10.3389/fpsyt.2022.1025346

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Copyright © 2023 Grimm, Mendez, Stertz, Meyer, Fries, Gandhi, Kanchi, Selvaraj, Teixeira, Kosten, Gunaratne, Coarfa and Walss-Bass.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Integrative analysis of miRNA–mRNA networks. (A) Pathway enrichment was carried out with the enriched gene targets of BA9 and blood miRNAs using the Gene Ontology Biological Processes compendium, with overlap of enriched pathways shown as a Venn diagram. (B) Top 20 common GOBP pathways between BA9 and blood miRNA targets. (C) List of GO terms enriched in the 549 significant pathways in BA9 miRNA targets. (D) List of GO terms enriched in the 1,043 pathways significant in blood miRNA targets. For panels (C,D), the percent of pathways associated with a GO term, odds-ratio, and –log10(FDR) are shown.