Table 1. Changes in Structural Parameters of the SOPC LNPs from SANS and DLS Measurementsa.
| SANS |
DLS |
|||||||
|---|---|---|---|---|---|---|---|---|
| pH | Radius (±6 Å) | Schulz Polydispersity (±0.02) | d (±0.5 Å) | ε (±0.5 Å) | γ (±2%) | Hydrodynamic Radius (±3 Å) | PDI (±0.01) | ZP (±3 mV) |
| 7.4 | 467 | 0.53 | 62.0 | 67.7 | –0.958 | 625 | 0.07 | –26.6 |
| 4.0 | 530 | 0.41 | 59.1 | 68.9 | –0.963 | 750 | 0.05 | 4.3 |
a
The table covers the hydrodynamic radius, size polydispersity (PDI), and zeta potential (ZP) measured by DLS, LNP radius, periodicity thickness (d), correlation length (ε), and amphiphile strength (γ) from SANS data analysis.