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. 2023 Jan 10;17(2):896–909. doi: 10.1021/acsnano.2c05286

Figure 3.

Figure 3

Transplantation with the PEP–TPP–mitochondria compound enhances respiration-associated mechanical function of cardiomyocytes. (A) Expression of OXPHOS complexes of cardiomyocytes after transplantation of mitochondria with and without PEP–TPP conjugation for 6 h. (B) OCR changes of cardiomyocytes transplanted with different mitochondria. (C) Statistical analysis of basal respiration in cardiomyocytes. (D) Resting cell length. (E) Maximal velocity of shortening (−dl/dt). (F) Time to peak shortening (TPS-s). (G) Peak shortening (% cell lengthening). (H) Maximal velocity of relengthening (+dl/dt). (I) Time to 90% relengthening (TR90-s). Mean ± SEM, *P < 0.05, **P < 0.01, ****P < 0.0001. Statistical analysis was carried out by a one-way ANOVA analysis followed by Tukey’s test for post hoc analysis.