Table 1.
Caregiver sample characteristics and proxy-reported patient characteristics
| Sample characteristic | Caregiversa (N = 36) |
General populationb (N = 36) |
|---|---|---|
| Mean (SD) | Mean (SD) | |
| Age | 56.3 (12.5) a | 57.5 (13.4) b |
| N (%) | N (%) | |
|---|---|---|
| Gender: female | 29 (81%) a | 29 (81%) b |
| Living situation: with partner/spouse | 34 (94%) | 36 (100%) b |
| Living situation: with relative | 2 (5%) a | 0 (0%) |
| Employment status: employed full-time | 5 (14%) | 5 (14%) |
| Employment status: employed part-time | 10 (28%) | 10 (28%) |
| Employment status: homemaker/retired/unemployed/other | 20 (56%) | 20 (56%) |
| Employment status: unable to work due to own health | 1 (3%) a | 1 (3%) b |
| Patient characteristic | Mean (SD) | |
|---|---|---|
| Time since diagnosis (years) | 5.76 (4.80) a | |
| Age | 59.00 (13.38) a |
| N (%) | ||
|---|---|---|
| Gender: male | 28 (78%) a | |
| Employment status: employed, full- or part-time | 6 (17%) | |
| Ambulatory status*: requires no assistance walking | 12 (33%) | |
| Ambulatory status*: requires assistance with walking | 21 (58%) | |
| Ambulatory status*: requires wheelchair | 2 (6%) | |
| Ambulatory status*: bedridden | 1 (3%) a | |
| Type of ATTRv: cardiomyopathy | 2 (6%) | |
| Type of ATTRv: polyneuropathy | 11 (31%) | |
| Type of ATTRv: cardiomyopathy and polyneuropathy | 20 (56%) a | |
| Type of ATTRv: other/not sure | 3 (8%) | |
| V-30 M status: V-30 M variant confirmed | 8 (22%) | |
| Symptoms: neuropathic symptom(s) reported | 36 (100%) a | |
| Symptoms: cardiac symptom(s) reported | 26 (72%) a | |
| Symptoms: gastrointestinal symptom(s) reported | 30 (83%) a |
aCharacteristics of the patient-caregiver aged 38 (n=1) and the patient aged 46 who the patient-caregiver was caring for
bCharacteristics of the matched control aged 38 (n=1)
*Requires no assistance walking, requires assistance with walking and requires wheelchair correspond to Coutinho stages 1, 2 and 3 respectively