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. 2023 Jan 26;18:17. doi: 10.1186/s13023-022-02601-5

Table 3.

EQ-5D-3L Utility and Disutility: general population, caregivers and caregivers by ambulatory status

EQ-5D-3L utilities
Caregivers versus general population N Mean SD
Total sample
General population 36 0.849 0.218
Caregivers 36 0.772 0.178
Excluding patient-caregivera
General population 35 0.871 0.122
Caregivers 35 0.778 0.219
Caregivers by ambulatory status N Mean SD
Requires no assistance walking 12 0.819 0.126
Requires assistance with walking 21 0.754 0.266
Requires wheelchair 2 0.787 0.087
Bedriddenb 1 0.585
Estimated EQ-5D-3L disutilitiesC by ambulatory status
Predictors in regression model Without covariates With covariates
Coefficient (disutility) SE Coefficient (disutility) SE
Total sample
General population Ref Ref
Requires no assistance walking  − 0.031 0.067  − 0.036 0.066
Requires assistance with walking  − 0.096 0.055  − 0.101 0.055
Requires wheelchair/bedridden  − 0.130 0.121  − 0.110 0.121
Age  − 0.003 0.002
Gender  − 0.059 0.061
Not employed vs. employed (ref.)  − 0.053 0.053
Excluding patient-caregivera
General population Ref Ref
Requires no assistance walking  − 0.053 0.060  − 0.036 0.066
Requires assistance with walking  − 0.118* 0.049  − 0.101 0.055
Requires wheelchair/bedridden  − 0.085 0.130  − 0.110 0.121
Age  − 0.003 0.002
Gender  − 0.059 0.061
Not employed vs. employed (ref.)  − 0.053 0.053

aSample excluding patient-caregiver (n=1) and corresponding matched control (n=1).

bThe caregiver utility value for the bedridden patient is that of the patient-caregiver (n=1).

cEstimated using Ordinary Least Squares (OLS) regression

*p<0.05