Table 2:
SLNB | ALND | SLNB + ALND | No Surgery | Chi-2 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Nb | % | Nb | % | Nb | % | Nb | % | p-value | ||
All patients | 352 | 1001 | 259 | 17 | ||||||
Period | P1 | 5 | 1.4 | 208 | 20.8 | 65 | 25.1 | 2 | 11.8 | <0.0001 |
P2 | 82 | 23.3 | 305 | 30.5 | 113 | 43.6 | 3 | 17.6 | ||
P3 | 265 | 75.3 | 488 | 48.8 | 81 | 31.3 | 12 | 70.6 | ||
Subtypes | Luminal A | 44 | 12.5 | 273 | 27.3 | 73 | 28.2 | 3 | 17.6 | <0.0001 |
Luminal B Her2− | 23 | 6.5 | 134 | 13.4 | 41 | 15.8 | 0 | 0 | ||
Luminal B Her2+ | 64 | 18.2 | 186 | 18.6 | 49 | 18.9 | 3 | 17.6 | ||
Her2+ | 45 | 12.8 | 147 | 14.7 | 25 | 9.7 | 3 | 17.6 | ||
Triple Negative | 176 | 50 | 259 | 25.9 | 70 | 27 | 8 | 47.1 | ||
Luminal Her2− Grade? | 0 | 0 | 2 | 0.2 | 1 | 0.4 | 0 | 0 | ||
cN stage | cN0 | 328 | 93.2 | 282 | 28.2 | 168 | 64.9 | 12 | 70.6 | <0.0001 |
cN1 | 23 | 6.5 | 702 | 70.1 | 88 | 30.4 | 4 | 23.5 | ||
cNx | 1 | 0.3 | 17 | 1.7 | 3 | 1.2 | 1 | 5.9 | ||
cT stage | cT0-1 | 82 | 23.3 | 129 | 12.9 | 24 | 9.3 | 5 | 29.4 | <0.0001 |
cT2 | 254 | 72.2 | 481 | 48.1 | 190 | 73.9 | 8 | 47.1 | ||
cT3 | 16 | 4.5 | 291 | 29.1 | 40 | 15.6 | 3 | 17.6 | ||
cT4 | 0 | 0 | 100 | 10 | 3 | 1.2 | 1 | 5.9 | ||
only cN0 patients | 328 | 282 | 168 | 12 | ||||||
Period | P1 | 5 | 1.5 | 69 | 24.5 | 46 | 27.4 | 1 | 8.3 | <0.0001 |
P2 | 76 | 23.2 | 54 | 19.1 | 65 | 38.7 | 1 | 8.3 | ||
P3 | 247 | 75.3 | 159 | 56.4 | 57 | 33.9 | 10 | 83.3 | ||
Subtypes | Luminal A | 43 | 13.1 | 90 | 31.9 | 46 | 27.4 | 2 | 16.7 | <0.0001 |
Luminal B Her2− | 23 | 7 | 28 | 9.9 | 26 | 15.5 | 0 | 0 | ||
Luminal B Her2+ | 61 | 18.6 | 46 | 16.3 | 33 | 19.6 | 3 | 25 | ||
Her2+ | 44 | 13.4 | 46 | 16.3 | 16 | 9.5 | 1 | 8.3 | ||
Triple Negative | 157 | 47.9 | 72 | 25.5 | 47 | 28 | 6 | 50 | ||
cT stage | cT0-1 | 77 | 23.5 | 50 | 17.7 | 18 | 10.7 | 5 | 41.7 | <0.0001 |
cT2 | 237 | 72.3 | 137 | 48.6 | 125 | 74.4 | 6 | 50 | ||
cT3 | 14 | 4.3 | 81 | 28.7 | 24 | 14.3 | 1 | 8.3 | ||
cT4 | 0 | 0 | 14 | 5 | 1 | 0.6 | 0 | 0 |
Abbreviations: cT, clinical tumor size stage; cN, clinical lymph node status; SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection