Table 8:
Significant associations between breast conservative surgery or mastectomy in univariate analysis.
Conservative | Mastectomy | Chi-2 | ||||
---|---|---|---|---|---|---|
Nb | % | Nb | % | p-value | ||
All patients | 733 | 45 | 896 | 55 | ||
Period | P1 | 103 | 14.1 | 177 | 19.8 | 0.002 |
P2 | 220 | 30 | 283 | 31.6 | ||
P3 | 410 | 55.9 | 436 | 48.7 | ||
Subtypes | Luminal A | 151 | 20.6 | 242 | 27 | <0.0001 |
Luminal B Her2− | 90 | 12.3 | 108 | 12.1 | ||
Luminal B Her2+ | 129 | 17.6 | 173 | 19.3 | ||
Her2+ | 76 | 10.4 | 144 | 16.1 | ||
Triple Negative | 285 | 38.9 | 228 | 25.4 | ||
Luminal Her2− Grade? | 2 | 0.3 | 1 | 0.1 | ||
cT stage | cT0-1 | 127 | 17.3 | 113 | 12.6 | <0.0001 |
cT2 | 509 | 69.4 | 426 | 47.5 | ||
cT3 | 85 | 11.6 | 265 | 29.6 | ||
cT4 | 12 | 1.6 | 92 | 10.3 | ||
cN stage | cN0 | 423 | 57.7 | 367 | 41 | <0.0001 |
cN1 | 302 | 41.2 | 515 | 57.4 | ||
cNx | 8 | 1.1 | 14 | 1.6 | ||
ypT | ypT0 | 246 | 33.6 | 274 | 30.6 | 0.274 |
ypTis | 70 | 9.5 | 77 | 8.6 | ||
ypT >= 1 | 417 | 56.9 | 545 | 60.8 | ||
pCR | Yes | 273 | 37.2 | 288 | 32.1 | 0.018 |
No | 460 | 62.8 | 608 | 67.9 |
Abbreviations: cT, clinical tumor size stage; cN, clinical lymph node status; ypT, pathologic tumor status after neoadjuvant chemotherapy; pCR, pathologic complete response.