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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Am J Perinatol. 2021 Nov 16;40(14):1585–1589. doi: 10.1055/s-0041-1739354

Fig. 3. 17-OHPC enhances LPS-mediated IL-10 production in THP-1-derived macrophages in vitro.

Fig. 3

17-OHPC and progesterone were exposed to THP-1-derived macrophages with LPS in varying concentrations. Supernatant IL-10 production by ELISA is recorded. One way analysis of variance with multiple comparisons and test for a linear trend was performed. The p-value represents the test for linear trend with variation of progesterone and 17-OHPC dose. R2 for 17-OHPC (A) is 0.746 and for progesterone (B) is 0.254. ELISA, enzyme-linked immunosorbent assay; IL-10, interleukin-10; LPS, lipopolysaccharide; 17-OHPC, 17α-hydroxyprogesterone caproate.