Table 4.
Participant Characteristics Classified According to Quartile Values of SIRI
| Variable | Overall | Q13(0.105–0.347) | Q14(0.347–0.452) | Q15(0.452–0.620) | Q16(0.620–4.687) | P |
|---|---|---|---|---|---|---|
| n=571 | n=144 | n=145 | n=147 | n=135 | ||
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
| Age (year) | 51.24 (4.49) | 50.89 (4.20) | 51.18 (4.46) | 51.46 (4.73) | 51.43 (4.59) | 0.686 |
| BMI (kg/m2) | 22.12 (2.62) | 22.20 (2.56) | 22.07 (2.74) | 22.29 (2.39) | 21.89 (2.81) | 0.598 |
| FSH (IU/L) | 72.21 (30.90) | 72.41 (27.73) | 73.58 (32.34) | 72.72 (30.52) | 69.98 (33.07) | 0.794 |
| LH (IU/L) | 34.18 (15.15) | 33.48 (12.78) | 34.96 (15.92) | 35.08 (15.87) | 33.12 (15.86) | 0.797 |
| E2 (pmol/L) | 132.20 (148.02) | 112.47 (90.01) | 122.69 (117.97) | 158.91 (207.26) | 134.37 (146.59) | 0.252 |
| Total T (nmol/L) | 1.16 (0.65) | 1.25 (0.66) | 1.08 (0.63) | 1.15 (0.56) | 1.17 (0.74) | 0.201 |
| TSH (IU/L) | 2.16 (1.42) | 1.99 (1.32) | 2.29 (1.57) | 2.25 (1.46) | 2.11 (1.30) | 0.265 |
| WBC (109/L)a | 5.28 (1.28) | 4.48 (0.87) | 4.98 (0.89) | 5.39 (1.05) | 6.31 (1.51) | < 0.001* |
| CRP (mg/L) | 1.47 (2.08) | 1.31 (2.69) | 1.25 (1.56) | 1.62 (1.81) | 1.69 (2.08) | 0.194 |
| Triglycerides (mmol/L)a | 1.28 (0.72) | 1.12 (0.61) | 1.32 (0.71) | 1.32 (0.69) | 1.36 (0.84) | 0.022* |
| HDL (mmol/L) | 1.55 (0.37) | 1.60 (0.34) | 1.54 (0.43) | 1.55 (0.34) | 1.54 (0.35) | 0.441 |
| LDL (mmol/L) | 3.01 (0.70) | 2.99 (0.82) | 3.07 (0.68) | 2.96 (0.66) | 3.01 (0.62) | 0.551 |
| HCY (mmol/L) | 11.80 (14.73) | 10.65 (2.88) | 13.16 (22.72) | 11.14 (4.20) | 12.29 (18.35) | 0.467 |
| Fasting glucose (mmol/L) | 5.19 (0.64) | 5.15 (0.50) | 5.18 (0.59) | 5.12 (0.41) | 5.33 (0.93) | 0.499 |
| Fasting insulin (pmol/L)a | 37.29 (20.14) | 31.68 (13.50) | 37.03 (21.53) | 41.31 (20.94) | 39.16 (22.37) | < 0.001* |
| HOMA-IRa | 1.27 (0.86) | 1.06 (0.52) | 1.26 (0.86) | 1.37 (0.74) | 1.39 (1.17) | 0.001* |
| The femoral neck BMD (g/cm2)a | 0.858 (0.108) | 0.870 (0.103) | 0.859 (0.116) | 0.875 (0.108) | 0.827 (0.100) | < 0.001* |
Notes: *Statistically significant difference. aMultiple comparisons had the statistically significant.
Abbreviations: SIRI, systemic inflammation response index; BMD, bone mineral density; CRP, C reactive protein; WBC, white blood cell; E2, estradiol; FSH, follicle stimulating hormone; LH, luteinizing hormone; TSH, thyroid-stimulating hormone; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HCY, homocysteine; BMI, body mass index; HOMA-IR, homeostatic model assessment index of insulin resistance.