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. 2023 Jan 26;18(1):e0277983. doi: 10.1371/journal.pone.0277983

Table 6. Normalized expression of core biosynthetic genes from biosynthetic gene clusters encoding secondary metabolites in B. velezensis E68.

Compound Core biosynthetic gene locus ID TPM$ in single culture TPM in dual culture
Surfactin GYA98_RS00790 41.62444 54.49393
GYA98_RS00795 39.72677 36.2239
GYA98_RS00800 10.51762 14.11884
GYA98_RS00810 49.16629 56.89863
GYA98_RS00815 55.97234 52.11947
GYA98_RS00820 77.41527 64.22825
Macrolactin H GYA98_RS06300 237.6562 90.06079
GYA98_RS06305 521.1573 100.0418
GYA98_RS06310 527.2992 96.8625
GYA98_RS06315 622.4262 113.8966
GYA98_RS06320 783.2996 181.6299
GYA98_RS06325 440.9877 118.3611
GYA98_RS06330 744.2543 223.779
Bacillaene GYA98_RS07605 410.8624 488.6164
GYA98_RS07610 420.911 373.5302
GYA98_RS07615 558.4976 478.7145
GYA98_RS07625 660.5088 360.3584
GYA98_RS07640 1183.568 361.8864
GYA98_RS07645 1198.974 260.8726
GYA98_RS07650 792.9114 160.4905
GYA98_RS07655 943.0376 233.3925
GYA98_RS07660 1074.126 305.5386
Bacillomycin D GYA98_RS08205 345.918 221.1193
GYA98_RS08210 604.1638 437.0655
GYA98_RS08215 565.6975 475.9636
GYA98_RS08220 277.014 215.3259
Fengycin GYA98_RS08300 3.060367 33.54516
GYA98_RS08315 2.122462 36.92852
GYA98_RS08335 571.6845 177.9275
GYA98_RS08340 543.9846 173.68
GYA98_RS08345 693.3596 238.2508
GYA98_RS08350 463.5909 187.7093
GYA98_RS08355 580.417 294.5991
GYA98_RS08365 281.5708 150.397
Difficidin GYA98_RS10060 1267.013 857.4785
GYA98_RS10065 1026.037 719.9703
GYA98_RS10070 899.1106 563.8603
GYA98_RS10075 1083.195 696.7137
GYA98_RS10080 901.9802 558.2665
GYA98_RS10085 912.1075 526.2694
GYA98_RS10090 1367.896 835.8435
GYA98_RS10095 1072.906 647.6522
GYA98_RS10100 1126.655 623.7472
GYA98_RS10105 510.1765 295.7482
GYA98_RS10110 953.4498 515.7316
GYA98_RS10135 573.8718 259.0871
Bacillibactin GYA98_RS13635 159.2003 49.03839
GYA98_RS13645 259.1896 116.4149
Amylocyclicin GYA98_RS13745 25433.92 14390.07
Bacilysin GYA98_RS16580 1691.767 989.5184

Genes were identified as core biosynthetic genes by antiSMASH.

$transcripts per million (TPM)