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. 2023 Jan 26;18(1):e0280954. doi: 10.1371/journal.pone.0280954

Table 1. Characteristics of studies in the scoping review (n = 64 studies).

Publication Location
Language Type CV focus Aspect Total women Objective
ACOG Practice Bulletin N. 72. 2006 [14] United States English practice guideline N comprehensive NA Approach to vaginitis
Akgun 2012 [15] Turkey English retrospective cohort Y association 4672 Relationship between CV and infertility
Amaral 2007 [16] Brazil English cross-sectional analytical N prevalence 155 Prevalence of abnormal flora and association between douching and abnormal flora
Anderson 2016 [17] United States English review Y comprehensive NA Overview of CV
Andrist 2001 [18] United States English review N comprehensive NA Approach to vaginal infections
Azevedo 2019 [19] Portugal English cross-sectional analytical N diagnosis 50 Impact vaginal sampling site has on wet mount microscopy results
Batashki 2009 [20] Bulgaria Bulgarian cross-sectional descriptive Y prevalence 1152 Prevalence of CV in women with vulvovaginal symptoms
Beghini 2015 [21] Brazil English cross-sectional analytical N diagnosis 209 Comparison of metabolites (D-lactic acid, L-lactic acid, EMMPRIN and MMP-8) in vaginal samples of women with vaginosis
Bibbo 1988 [22] United States English cross-sectional descriptive N prevalence 15000 Prevalence of abnormal microbiology in outpatient Pap samples
Cerikcioglu 2004 [23] Turkey English cross-sectional descriptive Y prevalence 210 Prevalence of CV in women with signs/symptoms of vulvovaginal candidiasis
Cibley 1991 [7] United States English review Y comprehensive NA Overview of CV
Demirezen 2003 [24] Turkey English cross-sectional descriptive Y prevalence 2947 Prevalence of CV in women with symptoms of vulvovaginal candidiasis
Donders 1999 [25] Belgium English review N diagnosis NA Classification of vaginal flora into grades based on quantity of lactobacilli
Donders 2007 [26] Belgium English review N comprehensive NA Diagnostic techniques for abnormal vaginal flora and characterization of abnormal vaginal flora
Donders 2010 [27] Belgium English review N comprehensive NA Management of recurrent vulvovaginal candidiasis
Edwards 2004 [28] United States English review N comprehensive NA Approach to infectious vaginitis
Fan 2010 [29] China Chinese Mandarin cross-sectional descriptive N prevalence 516 Characterization of clinical and microbiological findings of aerobic vaginitis
Faro 2004 [30] United States English review Y comprehensive NA Overview of CV
Fontan 2020 [31] Spain English cross-sectional analytical Y diagnosis 38 Evaluation of Lactobacillus crispatus as a marker of CV
Gaspar 2019 [32] Portugal English cross-sectional descriptive N diagnosis 24 Role of Lactobacillus crispatus in vaginal infections
Giraldo 2005 [33] Brazil Portuguese cross-sectional analytical N prevalence 97 Impact vaginal intercourse and douching has on vaginal microbiota 
Guevara 2011 [34] Venezuela Spanish review Y comprehensive NA Overview of CV
Gupta 2019 [35] India English review N comprehensive NA Analysis of the impact vaginal microbiome has on female health
Hacisalihoglu 2021 [36] Turkey English cross-sectional descriptive Y comprehensive 2932 Prevalence, diagnosis, and treatment of CV
Hay 2018 [37] United States English review N comprehensive NA Approach to vaginal discharge
Hills 2007 [38] United States English review Y comprehensive NA Overview of CV and lactobacillosis
Hu 2015 [39] China English cross-sectional descriptive Y diagnosis 108 Comparison of microbiological characteristics of CV and vulvovaginal candidiasis
Hutti 2000 [40] United States English review Y comprehensive NA Overview of CV
Jiang 2012 [41] China Chinese Mandarin cross-sectional descriptive N prevalence 1260 Prevalence of different types of vaginal infections in women attending an outpatient clinic
Kaufman 1989 [8] United States English review N comprehensive NA Overview of miscellaneous vaginal disorders
Korenek 2003 [42] United States English review Y comprehensive NA Overview of bacterial vaginosis, lactobacillosis, and CV
Lapina 2020 [43] Russia Russian prospective cohort N treatment 60 Impact of Zalain (vaginal suppositories) with Zalagel Intim (gel) post genital prolapse surgery on risk of vaginal dysbiosis
Ledger 2017 [44] United States English review Y comprehensive NA Overview of CV, aerobic vaginitis, and desquamative inflammatory vaginitis
MartinSaco 2019 [45] Spain English review N comprehensive NA Evidence review of lesser known vaginitis conditions
Mills 2017 [46] United States English review N comprehensive NA Approach to vaginitis
Moghaddam 2009 [47] Iran English case control N association 415 Association between types of Lactobacilli flora and vulvovaginal candidiasis
Mulley 2000 [48] United States English review N comprehensive NA Approach to vaginal discharge
Nasiell 1972 [49] Sweden English cross-sectional analytical N association 440 Association between lactobacilli/CV and cervical dysplasia/cervical cancer
Paavonen 1995 [50] Finland English review N comprehensive NA Approach to vulvodynia
Puri 2019 [51] India English cross-sectional descriptive Y prevalence 190 Prevalence of CV
Ramirez-Santos 2008 [52] Spain English review N comprehensive NA Approach to recurrent vulvovaginitis
Raykova 2018 [53] Bulgaria English cross-sectional descriptive Y prevalence 468 Prevalence of CV compared to vulvovaginal candidiasis and bacterial vaginosis in women presenting with vaginal discharge
Ricci 2010 [54] Chili Spanish review Y comprehensive NA Overview of CV
Rocchetti 2011 [55] Brazil English cross-sectional analytical N association 405 Prevalence and risk factors of group B streptococci in pregnant women
Sanches 2018 [56] Brazil English cross-sectional analytical Y diagnosis 24 Characterization of the vaginal lipids concentration in vaginal discharge of vulvovaginal candidiasis, CV and normal vaginal flora samples
Sanches 2020 [57] Brazil English cross-sectional analytical Y diagnosis 24 Clinical and laboratory characteristics to differentiate CV and vulvovaginal candidiasis
Secor 1992 [58] United States English review Y comprehensive NA Overview of CV
Shopova 2001 [59] Bulgaria Bulgarian review N comprehensive NA Overview of clinical and microbiological characteristics of lactobacillus
Shopova 2006 [60] Bulgaria Bulgarian case series Y comprehensive 47 Case series of women with CV
Silva 2014 [61] Brazil English retrospective cohort N association 3390 Factors associated with evolution of cervical intraepithelial lesions 
Suresh 2009 [62] India English review Y comprehensive NA Overview of CV
Vertolini 2014 [63] United States English review N comprehensive NA Review of lactobacillosis
Vieira-Baptista 2017 [64] Portugal English case control N association 291 Association between vaginal flora and vulvodynia
Vieira-Baptista 2017 [65] Portugal English cross-sectional analytical Y association 1022 Association between CV and cervical dysplasia/HPV
Vieira-Baptista 2019 [66] Portugal English review N comprehensive NA Overview of vaginitis
Vieira-Baptista 2020 [67] Portugal English review N comprehensive NA Critical analysis of current diagnostic approach for vaginitis
Vieira-Baptista 2021 [68] Portugal English review N diagnosis NA Establish evidence-based recommendations for wet mount microscopy
Voytik 2020 [10] United States English review Y comprehensive NA Evidence appraisal of CV
Wathne 1994 [69] Sweden English cross-sectional descriptive N prevalence 101 Comparison of clinical and microbiological findings in women with vaginal discharge
Xiao 2010 [70] China Chinese Mandarin review Y comprehensive NA Overview of CV
Xu 2019 [71] China English cross-sectional analytical Y diagnosis 75 Characterization of microbiome of women with CV with high-throughput sequencing
Yang 2017 [72] China English cross-sectional descriptive Y diagnosis 536 Clinical differences between CV and vulvovaginal candidiasis in women with recurring vulvovaginitis
Yang 2020 [73] China English cross sectional analytical Y diagnosis 149 Microbial composition and variation in lactobacillus microbiome in patients with CV compared to healthy controls
Zidovsky 1963 [74] Czech Republic English retrospective cohort Y association 953 Association between CV and fetal impairment