Table 2. HIV-1 subtypes and resistance mutations associated with analogous nucleoside/nucleotide reverse transcriptase inhibitors (NRTI), non-analogous nucleoside reverse transcriptase inhibitors (NNRTI) and protease inhibitors (PI).
| PW* | Subtype | Drug-resistant mutations | Other mutations | |||||
|---|---|---|---|---|---|---|---|---|
| NRTI | NNRTI | PI | NRTI | NNRTI | PI | |||
| Naive | 04G | B | - | - | - | - | - | - |
| 06G | B/F | - | - | - | - | - | - | |
| 09G | B | - | - | - | - | V108I | - | |
| 13G | K/F | - | - | - | - | - | - | |
| 14G | B | - | - | - | - | - | - | |
| 18G | B | - | - | - | - | - | - | |
| 19G | B | - | - | - | - | - | - | |
| 23G | B | - | - | - | - | - | - | |
| 25G | B | - | - | - | - | V179D | - | |
| 26G | B | - | - | - | - | - | - | |
| 33G | F | - | - | - | - | - | - | |
| 48G | B | - | - | - | - | - | - | |
| 52G | B | - | - | - | - | E138A | - | |
| 54G | B | - | - | - | - | - | - | |
| 68G | B | - | - | - | - | - | L10I, K20R | |
| 84G | B | - | - | - | - | - | - | |
| 95G | B | - | - | - | - | - | - | |
| 112G | B | - | - | - | - | - | - | |
| Exposed to cARVT | 2G | B | M184V | - | - | - | - | - |
| 05G | B | - | - | - | - | - | - | |
| 07G | B | D67N, T69D, K219R | - | - | - | - | - | |
| 08G | B | - | - | - | - | - | - | |
| 10G | B | M184V | - | - | - | P225H | - | |
| 12G | B | - | - | - | - | - | - | |
| 15G | B | - | - | - | - | - | - | |
| 16G | F/B | - | - | - | - | - | L10V, K20R | |
| 20G | B | - | - | M46IL | - | - | - | |
| 32G | B | - | - | - | - | - | - | |
| 35G | B | - | - | - | - | - | - | |
| 43G | F | - | - | - | - | - | - | |
| 53G | B | - | - | - | - | - | - | |
| 61G | B | - | - | - | - | E138A | - | |
| 66G | B | - | - | - | - | - | - | |
| 67G | B | - | - | - | - | - | - | |
| 96G | B | - | - | M46L | - | - | - | |
| 98G | B | D67N, T69N, K70R, M184V, T215F, K219EQ | - | I50L | - | - | - | |
| 110G | F/B | - | K103N | - | V75M | - | - | |
| 115G | B | - | - | - | - | - | L10V, K20R | |
cARVT = combined antiretroviral therapy; PW = pregnant women; NRTI = nucleoside/nucleotide reverse transcriptase inhibitors; NNRTI = non-analogous nucleoside reverse transcriptase inhibitors.