Table 1. Baseline characteristics of spontaneous regression within the study sample.
Patient characteristics* | Oral (n=46) | Esophageal (n=11) | Gastric (n=38) | Peritoneal (n=3) | Hepatobiliary (n=212) | Pancreatic (n=10) | Small bowel (n=10) | Colorectal (n=60) | Total (n=390) |
Age (Mean (SD)) | 61.2 (17.4) | 59.0 (16.2) | 60.1 (19.0) | 47.7 (15.9) | 64.7 (13.5) | 50.4 (18.2) | 51 (16.2) | 62.1 (15.0) | 63.1 (14.7) |
Age group (n (%)) | |||||||||
<19 | 1 (2.2%) | 0 | 1 (2.6%) | 0 | 0 | 0 | 0 | 1 (1.7%) | 3 (0.8%) |
19-34 | 3 (6.5%) | 1 (9.1%) | 2 (5.3%) | 0 | 6 (2.8%) | 2 (20.0%) | 1 (10.0%) | 1 (1.7%) | 16 (4.1%) |
35-44 | 1 (2.2%) | 1 (9.1%) | 7 (18.4%) | 2 (66.7%) | 6 (2.8%) | 1 (10.0%) | 2 (20.0%) | 7 (11.7%) | 27 (6.9%) |
45-54 | 11 (23.9%) | 1 (9.1%) | 2 (5.3%) | 0 | 21 (9.9%) | 1 (10.0%) | 1 (10.0%) | 7 (11.7%) | 44 (11.3%) |
55-64 | 8 (17.4%) | 4 (36.4%) | 10 (26.3%) | 0 | 49 (23.1%) | 2 (20.0%) | 5 (50.0%) | 17 (28.3%) | 95 (24.4%) |
65-74 | 9 (19.6%) | 2 (18.2%) | 5 (13.2%) | 1 (33.3%) | 82 (38.7%) | 1 (10.0%) | 1 (10.0%) | 13 (21.7%) | 114 (29.2%) |
75-84 | 11 (23.9%) | 2 (18.2%) | 10 (26.3%) | 0 | 43 (20.3% | 1 (10.0%) | 0 | 12 (20.0%) | 79 (20.3%) |
85+ | 2 (4.3%) | 0 | 1 (2.6%) | 0 | 4 (1.9%) | 0 | 0 | 2 (3.3%) | 9 (2.3%) |
Sex (n (%)) | |||||||||
Male | 25 (54.3%) | 8 (72.7%) | 23 (60.5%) | 2 (66.7%) | 168 (79.2%) | 6 (60.0%) | 5 (50.0%) | 35 (58.3%) | 272 (69.7%) |
Female | 21 (45.7%) | 3 (27.3%) | 15 (39.5%) | 1 (33.3%) | 44 (20.8%) | 4 (40.0%) | 5 (50.0%) | 25 (41.7%) | 118 (30.3%) |
Site of Regression (n (%)) | |||||||||
Primary tumor/Recurrence | 41 (89.1%) | 8 (72.7%) | 35 (92.1%) | 0 | 194 (91.5%) | 10 (100.0%) | 7 (70.0%) | 48 (80.0%) | 288 (73.8%) |
Lung metastases | 2 (4.3%) | 3 (27.3%) | 0 | 1 (33.3%) | 28 (13.2%) | 0 | 1 (10.0%) | 2 (3.3%) | 37 (9.5%) |
Liver metastases | 0 | 0 | 1 (2.6%) | 1 (33.3%) | 2 (0.9%) | 2 (20.0%) | 2 (20.0%) | 10 (16.7%) | 18 (4.6%) |
Lymph metastases | 5 (10.9%) | 2 (18.2%) | 1 (2.6%) | 0 | 2 (0.9%) | 0 | 3 (30.0%) | 2 (3.3%) | 15 (3.8%) |
Other metastases | 1 (2.2%) | 1 (9.1%) | 1 (2.6%) | 1 (33.3%) | 13 (6.1%) | 0 | 1 (10.0%) | 6 (10.0%) | 24 (6.2%) |
Extent of regression (n (%)) | |||||||||
Complete | 43 (93.5%) | 9 (81.8%) | 32 (84.2%) | 2 (66.7%) | 156 (73.6%) | 8 (80.0%) | 10 (100.0%) | 57 (95.0%) | 317 (81.3%) |
Partial | 3 (6.5%) | 2 (18.2%) | 6 (15.8%) | 1 (33.3%) | 56 (26.4%) | 2 (20.0%) | 0 | 3 (5.0%) | 73 (18.7%) |
Histological profile (n (%)) | |||||||||
Carcinoma | 11 (23.9%) | 8 (72.7%) | 8 (21.1%) | 0 | 198 (93.4%) | 9 (90.0%) | 1 (10.0%) | 54 (90.0%) | 289 (74.1%) |
Primary lymphoma | 28 (60.9%) | 1 (9.1%) | 24 (63.2%) | 0 | 4 (1.9%) | 0 | 6 (60.0%) | 4 (6.7%) | 67 (17.2%) |
NET | 1 (2.2%) | 0 | 6 (15.8%) | 0 | 2 (0.9%) | 1 (10.0%) | 1 (10.0%) | 1 (1.7%) | 12 (3.1%) |
Other | 6 (13.0%) | 2 (18.2%) | 0 | 3 (100.0%) | 8 (3.8%) | 0 | 2 (20.0%) | 1 (1.7%) | 22 (5.6%) |
Period of regression (n (%)) | |||||||||
<1 month | 4 (8.7%) | 0 | 3 (7.9%) | 0 | 6 (2.8%) | 0 | 0 | 0 | 13 (3.3%) |
1-1.5 months | 3 (6.5%) | 1 (9.1%) | 5 (13.2%) | 0 | 11 (5.2%) | 1 (10.0%) | 0 | 9 (15.0%) | 30 (7.7%) |
2-5 months | 2 (4.3%) | 2 (18.2%) | 6 (15.8%) | 1 (33.3%) | 27 (12.7%) | 0 | 3 (30.0%) | 13 (21.7%) | 54 (13.8%) |
6-11 months | 6 (13.0%) | 3 (27.3%) | 3 (7.9%) | 0 | 16 (7.5%) | 1 (10.0%) | 3 (30.0%) | 1 (1.7%) | 33 (8.5%) |
12-23 months | 6 (13.0%) | 2 (18.2%) | 5 (13.2%) | 0 | 41 (19.3%) | 2 (20.0%) | 0 | 9 (15.0%) | 65 (16.7%) |
24-35 months | 6 (13.0%) | 1 (9.1%) | 4 (10.5%) | 1 (33.3%) | 30 (14.2%) | 1 (10.0%) | 0 | 3 (5.0%) | 46 (11.8%) |
36-47 months | 5 (10.9%) | 0 | 2 (5.3%) | 0 | 14 (6.6%) | 1 (10.0%) | 1 (10.0%) | 5 (8.3%) | 28 (7.2%) |
48 months+ | 8 (17.4%) | 1 (9.1%) | 8 (21.1%) | 1 (33.3%) | 33 (15.6%) | 4 (40.0%) | 2 (20.0%) | 17 (28.3%) | 74 (19.0%) |
Unspecified | 6 (13.0%) | 1 (9.1%) | 2 (5.3%) | 0 | 34 (16.0%) | 0 | 1 (10.0%) | 3 (5.0%) | 47 (12.1%) |
Malignancy recurrence (n (%)) | |||||||||
Reported | 5 (10.9%) | 0 | 1 (2.6%) | 0 | 14 (6.6%) | 1 (10.0%) | 2 (20.0%) | 1 (1.7%) | 24 (6.2%) |
Not reported | 41 (89.1%) | 11 (100.0%) | 37 (97.4%) | 3 (100.0%) | 198 (93.4%) | 9 (90.0%) | 8 (80.0%) | 59 (98.3%) | 366 (93.8%) |