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. 2023 Jan 12;13:947622. doi: 10.3389/fpsyt.2022.947622

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Copyright © 2023 Singleton, Wang, Mithoefer, Hanlon, George, Mithoefer, Mithoefer, Coker, Yazar-Klosinski, Emerson, Doblin and Kuceyeski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Paired t-statistics shown for differences in functional connectivity between all brain regions of interest during the task fMRI scan involving neutral and trauma memory audio listening (N = 9; baseline > follow-up; *two-sided uncorrected p < 0.05; **pFDR < 0.05, corrected). (B) Pearson correlation values between changes in ROI functional connectivity and reduction in CAPS scores. Changes were calculated as follow-up values minus baseline values. (N = 9; *uncorrected p < 0.05; **pFDR < 0.05) Age and mean FD difference between baseline and follow-up were included as covariates of non-interest. (C) Scatter plots of the three correlations that remained significant after corrections for multiple comparisons (i.e., pFDR < 0.05). Red marker = female. Blue marker = male.