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Pharmacodynamics and safety in elderly and nonelderly subjects.
| Group | Dosage (mg/kg) | The median loss-of-consciousness time (min) | Mean BISpeak | The median times to full alertness (min) | Adverse events N (%) |
|---|---|---|---|---|---|
| Elderly | 0.2 | 2.54 | 60.1 | 6.02 | 3 (37.5) |
| 0.3 | 2.07 | 58.5 | 14.01 | 2 (25.0) | |
| 0.4 | 1.13 | 58.1 | 11.99 | 4 (50.0) | |
| Nonelderly | 0.4 | 1.15 | 48.5 | 10.03 | 1 (12.5) |
Notes: data from Li et al. [40]. Abbreviations: BISpeak: peak bispectral index value.
