Table 1.
Descriptive Characterization of the HABS-HD Sample Included in the Analyses
| Total Cohort N = 1 328 |
Mexican American N = 669 |
Non-Hispanic White N = 659 |
Statistic | |
|---|---|---|---|---|
| Age | 66.10 (8.51) | 68.92 (8.33) | 63.23(7.70) | F = 166.95, p < .001 |
| Education | 12.68 (4.7) | 15.59 (2.58) | 9.71 (4.54) | F = 847.59, p < .001 |
| Gender (% male) | 36% | 30% | 41% | χ 2 = 18.52, p < .001 |
| MMSE | 28.07 (2.30) | 29.19 (1.01) | 26.94 (2.66) | F = 419.06, p < .001 |
| Tug (s) | 9.66 (2.30) | 9.39 (2.03) | 9.94 (2.51) | F = 18.29, p < .001 |
| SPPB total | 10.88 (1.82) | 11.04 (1.68) | 10.72 (2.51) | F = 9.71, p < .001 |
| Aβ 40 pg/mL | 250.81 (65.93) | 264.98 (64.36) | 236.42 (64.42) | F = 62.63, p < .001 |
| Aβ 42 pg/mL | 11.99 (3.25) | 12.22 (3.12) | 11.77 (3.36) | F = 6.03, p = .014 |
| Tau pg/mL | 2.44 (.928) | 2.33 (.933) | 6.39 (.911) | F = 17.86, p < .001 |
| NfL pg/mL | 18.18 (11.37) | 19.87 (11.00) | 16.46 (11.48) | F = 29.23, p < .001 |
| Hypertension (% yes) | 61.8% | 65.4% | 58.3% | χ 2 = 7.10, p < .008 |
| Hyperlipidemia (% yes) | 64.6% | 66.6% | 63.1% | χ 2 = 1.38, p < .001 |
| Diabetes mellitus (% yes) | 23.3% | 35.0% | 11.8% | χ 2 = 18.52, p < .001 |
Notes: Aβ40 = plasma beta amyloid 40; Aβ42 = plasma beta amyloid 42; MMSE = Mini Mental State Examination; NfL = plasma neurofilament light; SPPB = Short Physical Performance Battery; tau = plasma total tau. All p values < .005.