Table.
Characteristics of the participants from the UK Biobank study (baseline 2006–10) and the HeSSup study, Finland (baseline 1998)
| UK Biobank (n=456 905) | HeSSup (n=18 468) | |
|---|---|---|
| Sex | ||
| Female | 249 586 (54·6%) | 11 367 (61·5%) |
| Male | 207 319 (45·4%) | 7101 (38·5%) |
| Age, years | ||
| Mean (SD) | 56·5 (8·1) | 42·5 (11·4) |
| Median (IQR) | 58·0 (50·0–63·0 ) | 45·0 (35·0–55·0 ) |
| Age groups, years | ||
| 0–49 | 107 242 (23·5%) | 4588 (24·8%) |
| 50–59 | 152 895 (33·5%) | 8787 (47·6%) |
| 60 or older | 196 768 (43·1%) | 5093 (27·6%) |
| Ethnicity | ||
| White | 431 725/455 363 (94·8%) | .. |
| Other | 23 638/455 363 (5·2%) | .. |
| Missing | 1542 (0·3%) | .. |
| Education | ||
| Low | 74 631/448 320 (16·6%) | 4175/18 370 (22·7%) |
| Intermediate | 224 141/448 320 (50·0%) | 9185/18 370 (50·0%) |
| High | 149 548/448 320 (33·4%) | 5010/18 370 (27·3%) |
| Missing | 8585 (1·9%) | 98 (0·5%) |
| Townsend index tertile | ||
| Bottom | 154 786/456 341 (33·9%) | .. |
| Intermediate | 153 185/456 341 (33·6%) | .. |
| Top | 148 370/456 341 (32·5%) | .. |
| Missing | 564 (0·1%) | .. |
| Alcohol consumption | ||
| Low | 255 247/456 556 (55·9%) | 6030/18 415 (32·7%) |
| High | 201 309/456 556 (44·1%) | 12 385/18 415 (67·3%) |
| Missing | 349 (0·1%) | 53 (0·3%) |
| Current smoker | ||
| No | 408 708/455 295 (89·8%) | 5515/8898 (62·0%) |
| Yes | 46 587/455 295 (10·2%) | 3383/8898 (38·0%) |
| Missing | 1610 (0·4%) | 9570 (51·8%) |
| Physical activity | ||
| Low | 250 795/420 802 (59·6%) | 9786/18 345 (53·3%) |
| High | 170 007/420 802 (40·4%) | 8559/18 345 (46·7%) |
| Missing | 36 103 (7·9%) | 123 (0·7%) |
| BMI category | ||
| Normal weight | 149 915/446 101 (33·6%) | 9695/18 346 (52·8%) |
| Overweight | 190 555/446 101 (42·7%) | 6195/18 346 (33·8%) |
| Obese | 105 631/446 101 (23·7%) | 2456/18 346 (13·4%) |
| Missing | 10 805 (2·4%) | 122 (0·7%) |
| BMI | ||
| Mean (SD) | 27·3 (4·7) | 25·4 (4·5) |
| Missing | 10 805 (2·4%) | 122 (0·7%) |
| Depressed mood* | ||
| Low | 415 836/436 658 (95·2%) | 17 135/18 097 (94·7%) |
| High | 20 822/436 658 (4·8%) | 962/18 097 (5·3%) |
| Missing | 20 247 (4·4%) | 371 (2·0%) |
| Long-term illness | ||
| No | 224 804/443 289 (50·7%) | 6177/18 362 (33·6%) |
| Yes | 218 485/443 289 (49·3%) | 12 185/18 362 (66·4%) |
| Missing | 13 616 (3·0%) | 106 (0·6%) |
| High C-reactive protein (>3 mg/L) | ||
| No | 333 223/426 655 (78·1%) | .. |
| Yes | 93 432/426 655 (21·9%) | .. |
| Missing | 30 250 (6·6%) | .. |
| Socially isolated | ||
| No | 407 686/448 114 (91·0%) | 16 600/18 376 (90·3%) |
| Yes | 40 428/448 114 (9·0%) | 1776/18 376 (9·7%) |
| Missing | 8791 (1·9%) | 92 (0·5%) |
| Feeling lonely | ||
| No | 409 141/436 001 (93·8%) | 13 830/18 296 (75·6%) |
| Yes | 26 860/436 001 (6·2%) | 4466/18 296 (24·4%) |
| Missing | 20 904 (4·6%) | 172 (0·9%) |
| Follow-up time from baseline, years | ||
| Mean (SD) | 8·5 (1·9) | 9·8 (1·3) |
| Median (IQR) | 8·9 (8·0–9·6 ) | 10·0 (10·0–10·1 ) |
Data are n (%) or n/N (%), unless otherwise specified. HeSSup=Finnish Health and Social Support study.
*
Based on the frequency of depressed mood in the previous 2 weeks from the Patient Health Questionnaire in the UK Biobank study and on the Beck Depression inventory with a cutoff of 18 or more in the HeSSup study.