Table 1.

Data extraction for included study

Author, year	PMID	Type of study	Country	Study time period	Population	Number of procedures	Patients with AP and IE	Patients with AP and w/o IE	Patients w/o AP and IE	Patients w/o AP and w/o IE
Tubiana, 2017	28,882,817	Cohort study	France	2008–2014	Adults aged more than 18 years with prosthetic heart valves and undergoing invasive dental procedures	103,463	4	52,276	10	51,173

Tubiana et al. study includes adults with prosthetic heart valves who undergo invasive and non-invasive dental procedures. For the analysis, we considered only the invasive dental procedures. The study describes the total number of patients and the total number of dental procedures. It must be noted, however, that a few patients received multiple dental procedures during the study periods. For this reason, we considered the total number of dental procedures, and not solely the number of patients

AP antibiotic prophylaxis; IE infective endocarditis; w/o with or without