Table 1.
Phenotypic prevalence in the UK Biobank across and by sexes.
Both sexes | Men | Women | |||||||
---|---|---|---|---|---|---|---|---|---|
Without | With | Without | With | Without | With | ||||
Phenotypes | N | N | % | N | N | % | N | N | % |
Eating disorder | 124,092 | 1,489 | 1.19 | 54,488 | 116 | 0.21 | 69,604 | 1,373 | 1.93 |
Anorexia | 124,886 | 750 | 0.6 | 54,583 | 35 | 0.06 | 70,303 | 715 | 1.01 |
Anxiety | 69,555 | 12,337 | 15.06 | 34,437 | 4,219 | 10.91 | 35,118 | 8,118 | 18.78 |
Social anxiety | 117,099 | 1,412 | 1.19 | 50,835 | 654 | 1.27 | 66,264 | 758 | 1.13 |
Depression ever | 22,872 | 11,556 | 33.57 | 11,678 | 3,765 | 24.38 | 11,194 | 7,791 | 41.04 |
Probable depression | 86,282 | 30,995 | 26.43 | 43,254 | 10,970 | 20.23 | 43,028 | 20,025 | 31.76 |
Bipolar disorder | 30,035 | 226 | 0.75 | 14,494 | 108 | 0.74 | 15,541 | 118 | 0.75 |
Schizophrenia | 125,387 | 194 | 0.15 | 54,497 | 107 | 0.2 | 70,890 | 87 | 0.12 |
Self-harm thought or action | 220,343 | 41,079 | 15.71 | 103,443 | 15,215 | 12.82 | 116,900 | 25,864 | 18.12 |
Post-traumatic stress disorder | 117,290 | 7,820 | 6.25 | 51,826 | 2,626 | 4.82 | 65,464 | 5,194 | 7.35 |
Obsessiveācompulsive disorder | 156,192 | 1,268 | 0.81 | 67,781 | 400 | 0.59 | 88,411 | 606 | 0.68 |
Alcohol hazardous substance use or dependence | 117,083 | 6,591 | 5.33 | 49,594 | 4,072 | 7.59 | 67,489 | 2,519 | 3.6 |
Other hazardous substance use or dependence | 258,625 | 2,760 | 1.06 | 117,119 | 1,520 | 1.28 | 141,506 | 1,240 | 0.87 |
Cannabis use ever | 97,040 | 28,375 | 22.62 | 40,330 | 14,195 | 26.03 | 56,710 | 14,180 | 20 |
General allergy | 73,287 | 29,550 | 28.73 | 32,990 | 12,538 | 27.54 | 40,297 | 17,012 | 29.68 |
Asthma | 86,918 | 15,919 | 15.48 | 38,860 | 6,668 | 14.65 | 48,058 | 9,251 | 16.14 |
Hay fever rhinitis | 450,094 | 51,200 | 10.21 | 205,755 | 22,680 | 9.93 | 244,339 | 28,520 | 10.45 |
Other allergies | 489,588 | 11,682 | 2.33 | 224,543 | 3,880 | 1.7 | 265,045 | 7,802 | 2.86 |
Myopia | 76,190 | 33,881 | 30.78 | 34,734 | 15,489 | 30.8 | 41,456 | 18,392 | 30.7 |
Eczema | 252,947 | 8,448 | 3.23 | 114,743 | 3,902 | 3.29 | 138,204 | 4,546 | 3.18 |
Insomnia | 57,376 | 204,142 | 78.06 | 32,753 | 85,948 | 72.41 | 24,623 | 118,194 | 82.76 |
Loneliness | 452,782 | 23,105 | 4.86 | 204,356 | 11,782 | 5.45 | 248,426 | 11,323 | 4.36 |
Social isolation | 444,466 | 45,053 | 9.2 | 201,014 | 21,856 | 9.81 | 243,452 | 23,197 | 8.7 |
Chronotype (more evening) | 145,500 | 87,667 | 37.6 | 63,275 | 39,521 | 38.45 | 82,225 | 48,146 | 36.93 |
Same-sex sexual behavior | 15,757 | 432,740 | 96.49 | 8,873 | 197,539 | 95.7 | 6,884 | 235,201 | 97.16 |
Adulthood abuse | 20,479 | 20,479 | 16.32 | 4,701 | 4,701 | 8.62 | 15,778 | 15,778 | 22.25 |
Adulthood stressors | 51,167 | 51,167 | 40.91 | 21,289 | 21,289 | 39.12 | 29,878 | 29,878 | 42.28 |
Catastrophic trauma | 63,893 | 63,893 | 50.88 | 30,748 | 30,748 | 56.31 | 33,145 | 33,145 | 46.7 |
Childhood abuse | 14,060 | 14,060 | 11.2 | 5,387 | 5,387 | 9.87 | 8,673 | 8,673 | 12.22 |
Childhood stressors | 42,779 | 42,779 | 34.07 | 17,770 | 17,770 | 32.54 | 25,009 | 25,009 | 35.24 |
Note. Probable depression and cannabis use are ordinal but here reflect the prevalence of ever meeting the criteria regardless of severity.