Table 3.

Variables associated with loss of ambulation and deat

Variables associated with loss of ambulation
Variable	Full-time wheelchair/confined to bed	Ambulant	P value
FTD	23.5% (12/51)	11.6% (20/172)	0.03*
FVC <50%	35.5% (11/31)	6.0% (5/84)	<0.001†
Distal lower limb weakness	88.5% (46/52)	72.2% (117/162)	0.02*
Proximal lower limb weakness	98.1% (51/52)	86.5% (148/171)	0.02†
Axial weakness	69.6% (32/46)	49.0% (73/149)	0.03*
Dysautonomia	41.0% (16/39)	17.4% (26/149)	0.002*
Variables associated with death
Variable	Deceased	Alive	p value
FTD	27.8% (10/36)	10.8% (17/157)	0.02†
FVC <50%	35.3% (6/17)	11.0% (9/82)	0.02†
Dysphagia	31.4% (11/35)	16.3% (24/147)	0.04*
Drop-head	29.4% (10/34)	9.5% (14/147)	0.002†
Full-time wheelchair user/confined to bed	47.2% (17/36)	19.6% (30/153)	0.001*

^*χ² test.

^†Fisher’s exact test.

FTD, frontotemporal dementia; FVC, forced vital capacity.