Figure 1.

Activity of quercetin on the promastigote of L. (V.) brazilliensis. Promastigotes were cultivated in Schneider’s medium supplemented with 20% fetal bovine serum (FBS) at 27°C for 96 h, in the absence or presence of quercetin (indicated concentrations). The number of parasites was determined daily by counting in a Neubauer chamber. Controls were promastigotes cultured with a vehicle [0.02% dimethylsulfoxide (DMSO)] or 6 µM miltefosine as a reference drug. The data presented are representative of three independent experiments performed in triplicate. Mean ± SD, n = 3. **p < 0.01, ***p < 0.001 (difference compared to DMSO or medium).