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. 2023 Jan 13;13:1089987. doi: 10.3389/fimmu.2022.1089987

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Copyright © 2023 Lo Conte, Antonini Cencicchio, Ulaszewska, Nobili, Cosorich, Ferrarese, Massimino, Andolfo, Ungaro, Mancini and Falcone

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gut microbiota profiles of AID and STD-fed NOD mice. Microbiota isolated from luminal content and brushed intestinal mucosa of AID or STD-fed NOD mice at 12 weeks of age (n=6 per group) was assessed by 16S Amplicon Sequencinq of DNA and analysed with QIIME software. (A) alpha-diversity in AID vs STD-diet fed NOD mice based on Shannon index. (B) Differentially expressed bacterial species between AID and STD diet fed NOD mice. (C) Heatmap of selected differentially represented bacterial species in AID vs STD-diet fed NOD mice. (D) Relative abundance of selected differentially represented bacterial species in AID vs STD-fed NOD mice.