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. 2023 Jan 13;13:1080633. doi: 10.3389/fendo.2022.1080633

Table 3.

Maternal characteristics, lipid profiles and glucose metabolism indices in different QUICKI subgroups.

Characteristics IR-Q1 N=783 IR-Q2a N=155 IR-Q3a N=142 IR-Q4a N=154
Maternal age, years 31.42 ± 4.24 32.30 ± 4.76* 31.25 ± 3.91 31.76 ± 4.41
BMI, kg/m2 20.43 ± 2.33 23.83 ± 3.31** 21.98 ± 3.04** 21.53 ± 2.27**
Conception by IVF, n (%) 134 (17.1) 25 (16.1) 29 (20.4) 33 (21.4)
Smoking, n (%) 5 (0.6) 3 (1.9) 3 (2.1) 1 (0.6)
Family history of diabetes mellitus, n (%) 34 (4.3) 11 (7.1) 9 (6.3) 12 (7.8)
Multiparous, n (%) 245 (31.3) 62 (40.0)* 50 (35.2) 55 (35.7)
Blood tests in the first trimester
TC, mmol/L 4.91 ± 0.77 5.19 ± 0.84** 5.01 ± 0.83 5.02 ± 1.05
TG, mmol/L 1.26 ± 0.49 1.73 ± 0.68** 1.48 ± 0.54** 1.44 ± 0.45**
HDL-c, mmol/L 1.83 ± 0.32 1.71 ± 0.34** 1.73 ± 0.33** 1.72 ± 0.29**
LDL-c, mmol/L 2.71 ± 0.52 2.97 ± 0.58** 2.86 ± 0.56** 2.87 ± 0.76**
HbAlc, % 5.12 ± 0.29 5.20 ± 0.33** 5.11 ± 0.35 5.19 ± 0.31**
FPG, mmol/L 4.27 ± 0.32 4.49 ± 0.36** 4.58 ± 0.34** 4.31 ± 0.33
FINS, μU/mL 5.05 ± 1.65 12.32 ± 4.05** 10.24 ± 2.62** 6.51 ± 1.51**
Blood tests in the second trimester
TC, mmol/L 6.32 ± 1.05 6.28 ± 1.12 6.35 ± 1.12 6.40 ± 1.24
TG, mmol/L 1.96 ± 0.72 2.55 ± 1.01** 2.35 ± 0.87** 2.41 ± 0.90**
HDL-c, mmol/L 2.11 ± 0.37 1.99 ± 0.35** 2.03 ± 0.37* 2.02 ± 0.35**
LDL-c, mmol/L 3.58 ± 0.73 3.56 ± 0.81 3.65 ± 0.76 3.69 ± 1.02
HbAlc, % 4.83 ± 0.30 5.05 ± 0.34** 4.85 ± 0.28 4.96 ± 0.33**
FINS, μU/mL 6.41 ± 1.86 14.88 ± 5.03** 7.78 ± 1.59** 12.19 ± 2.29**
Oral glucose test result
FPG, mmol/L 4.21 ± 0.30 4.60 ± 0.40** 4.33 ± 0.30** 4.51 ± 0.37**
1-h PG, mmol/L 7.71 ± 1.58 8.82 ± 1.71** 7.77 ± 1.63 8.27 ± 1.82**
2-h PG, mmol/L 6.66 ± 1.37 7.53 ± 1.43** 6.84 ± 1.35 7.14 ± 1.43**

a In comparison with IR-Q1 group; *P < 0.05; **P < 0.01.