FIG. 1.

Effect of 6-OHDA treatment on plasma and splenic NE contents. Mice were injected intraperitoneally with 6-OHDA (solid bars) or the vehicle (open bars), and then blood and spleens were removed 48 h later. The NE concentrations in plasma (A) and spleen homogenates (B) were measured. Each result is the mean ± standard deviation based on three mice. An asterisk indicates that a value is significantly different from the value obtained for the vehicle-treated mice (P < 0.05). The results were reproduced in three repeated experiments.