FIG. 3.

Abrogation of the effect of 6-OHDA by desipramine. Mice were injected with desipramine 30 min before 6-OHDA treatment and were infected with 5 × 10⁴ CFU of L. monocytogenes 48 h later. The numbers of bacteria in the spleens (A) and livers (B) were determined on day 4 after infection. Each result is the mean ± standard deviation based on three mice. An asterisk indicates that a value is significantly different from the value obtained for the vehicle-treated mice (P < 0.05). The results were reproduced in three repeated experiments.