Skip to main content
. 2023 Jan 20;46(1):48–56. doi: 10.14348/molcells.2023.0003

Table 1.

List of representative mRNAs with 3’UTR-mediated control

Transcript RNA-binding proteins Control Function Reference
Hunchback Pumilio
Nanos
Brat
Translation repression Embryonic axis formation in Drosophila (Kuersten and Goodwin, 2003)
UCP1 CPEB2 Translation activation Maintain body temperature (Chen et al., 2018)
CaMK2A Mub Localization translation Control learning and memory in neuron (Broix et al., 2021; Chen et al., 2022)
ACTB IGF2BP1
PAT1
Stabilization local-translation Constituent of the cytoskeleton for structural support and movement in neuron (Wu et al., 2020)
Oskar Bruno
Hrp48
RNP granule formation
Translation
Embryonic patterning and germline formation in Drosophila (Bose et al., 2022; Jambor et al., 2014)
DMPK CUG-BP2 mRNA export
Translation
Maintenance of the myelin sheath (Amack and Mahadevan, 2001; Taneja et al., 1995)
n-myc
c-fos
ELAV like RNA binding protein family ARE-mediated mRNA stabilization Cellular growth in neuroblastoma (Chagnovich and Cohn, 1996; Chagnovich et al., 1996)
P21 WAF1 SRSF3 Translation repression Regulator of cell cycle and senescence (Kim et al., 2022)
COX-2 HuR
b-catenin
mRNA stabilization
Translation activation
Cellular proliferation and tumorigenesis (Kim et al., 2012; Lee and Jeong, 2006)
HHS Vulnerability Disclosure