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. 2022 Dec 20:10.1111/jocn.16326. Online ahead of print. doi: 10.1111/jocn.16326

TABLE 1.

Primary articles reporting long‐term symptoms of COVID‐19

Author and Year Type of study Study population Long‐term symptoms Timeline of the assessment of symptoms/outcomes
Carfì et al. (2020) Cross‐sectional study 143 patients who were discharged from the hospital after recovery from COVID‐19

Fatigue (53.1%)

Dyspnoea (43.4%)

Joint pain (27.3%)

Chest pain (21.7%)

The symptoms were assessed a mean of 60.3 (SD, 13.6) days after onset of the first COVID‐19 symptom
Davis et al. (2021) Cross‐sectional study 3762 respondents with suspected or confirmed COVID‐19 infection

Fatigue (86.7%)

Decreased cognition or memory (88%)

Relapses in symptoms due to physical/mental activity or stress (85.9%)

>91% of respondents took a time to recovery that exceeded 35 weeks
Garrigues et al. (2020) Cross‐sectional, study 120 patients

Fatigue (55%)

Dyspnoea (42%)

Memory Loss (34%)

Problems concentrating (28%)

Sleep disorders (30.8%)

Post‐discharge persistent symptoms were assessed more than 100 days after their admission
Ladds et al. (2020) Qualitative research design (Focus groups and individual interviews) 114 participants Nerve issues, fatigue, exhaustion, ‘brain fog’, decreased ability for daily activities NA
Mandal et al. (2021) Cross‐sectional study 384 patients followed a median 54 days post discharge

Fatigue (69%)

Breathlessness (53%)

Cough (34%)

Depression (15%)

38% of chest radiographs stayed abnormal and 9% deteriorated

4–6 weeks post‐discharge
Sudre et al. (2020) Prospective observational cohort study 4,182 incident cases of COVID‐19 were analyzed in which individuals self‐reported their symptoms

Most commonly reported symptoms were the following:

Fatigue (97.7%) and Intermittent headaches (91.2%)

Data gathered from COVID‐19 infected persons using app from March 24‐September 2, 2022
Taboada et al. (2021) Cross‐sectional study 91 participants previously admitted to COVID‐19 ICU

Difficulty breathing (57%)

Physical weakness (37%)

Muscle pain (37%)

Joint pain (29%)

Moderately anxious or depressed (41.8%)

Extremely anxious or depressed (4.4%)

6 months after ICU discharge