TABLE 3.
Gene products unique to M. avium identified via subtractive hybridization
| Gene product | Homolog | % Identity/% similarity/ no. of amino acids | Description/function |
|---|---|---|---|
| JAM1 | M. tuberculosis Rv0227c | 74/80/389 | Possible membrane protein/unknown |
| M. leprae CAA18554.1 | 67/76/446 | Putative membrane protein/unknown | |
| JAM2 | M. tuberculosis Rv0226c | 58/61/259 | Probable membrane protein/unknown |
| M. leprae CAA18553.1 | 50/55/276 | Putative membrane protein/unknown | |
| JAM3 | M. tuberculosis Rv1779c | 35/41/289 | PPE family of proteins/unknown |
| JAM4 | M. tuberculosis Zwf | 91/95/483 | GGPD/oxidative stress |
| S. coelicolor CAB50762.1 | 69/79/483 | G6PD/oxidative stress | |
| JAM5 | M. tuberculosis Rv0160 | 65/75/378 | Unknown/unknown |
| B. subtilis YciC | 25/41/359 | Zn Uptake/Zn homeostasis | |
| JAM6 | M. tuberculosis Rv0286 | 32/40/148 | PPE family of protens/unknown |
| JAM7 | M. tuberculosis LipP | 78/83/320 | Probable esterase/lipid biosynthesis |
| S. chrysomallus EstA | 45/55/317 | Esterase/unknown | |
| JAM8 | M. tuberculosis Tig | 96/97/59 | Chaperone-proylisomerase/protein folding and secretion |
| S. coelicolor Tig | 54/74/59 | Chaperone-proylisomerase/protein folding and secretion | |
| JAM9 | M. tuberculosis Rv1463 | 67/72/253 | ABC transporter/ATP-binding protein |
| M. leprae CAB16169.1 | 64/69/253 | ABC transporter/ATP-binding protein | |
| JAM10 | M. tuberculosis NifS | 88/91/100 | Protein modification/Fe-S cluster formation |
| M. leprae NifS | 82/94/100 | Protein modification/Fe-S cluster formation | |
| JAM11 | M. tuberculosis Rv1871c | 77/81/109 | Unknown/unknown |
| S. coelicolor CAB88434.1 | 56/66/112 | Unknown/unknown | |
| JAM12 | M. smegmatis LonA | 85/92/227 | ATP-dependent protease/protein degradation |
| M. xanthus LonA | 49/64/276 | ATP-dependent protease/protein degradation | |
| JAM13 | M. tuberculosis LprL | 28/47/374 | Membrane lipoprotein/unknown |
| M. tuberculosis LprK | 25/42/261 | Membrane lipoprotein/unknown | |
| JAM14 | M. tuberculosis Rv0453 | 30/37/147 | PPE family of proteins/unknown |
| JAM15 | S. coelicolor CAB88970 | 34/52/292 | Regulatory protein/regulation of secondary metabolites |
| M. tuberculosis Rv1204 | 25/36/526 | Possible secreted protein/unknown | |
| JAM16 | M. tuberculosis Rv3254 | 40/45/344 | Unknown/unknown |
| S. coelicolor CAA20504 | 36/50/357 | Possible secreted protein/unknown | |
| JAM17 | S. coelicolor CAB56384 | 57/67/403 | Probable peptidase/protein degradation |
| P. aeruginosa AAG06310 | 38/51/367 | Probable hydrolase/unknown | |
| JAM18 | S. coelicolor CAB51980 | 26/37/412 | Putative Na/H exchanger/unknown |
| M. tuberculosis YjcE | 24/37/538 | Putative Na/H exchanger/unknown | |
| JAM19 | M. leprae CAB09639 | 81/83/285 | Oxidoreductase/unknown |
| D. radiodurans AAF11444.1 | 57/72/280 | Oxidoreductase/unknown | |
| JAM20 | M. tuberculosis Rv0560c | 68/87/250 | Probable methyltransferase/unknown |
| M. tuberculosis Rv3699 | 52/64/108 | Probable methyltransferase/unknown | |
| JAM21 | S. lividans AAC25767 | 61/72/145 | Unknown/unknown |
| M. tuberculosis Rv1558 | 56/71/139 | Unknown/unknown |