Table 1.

Total SARS‐CoV‐2 RNA signal detection in hospital‐wastewater samples as a function of proximity to a declared outbreak

Hospital	Total SARS‐CoV‐2 RNA signal measured by	Measurement	Outbreak‐free periods vs. outbreaks [median (IQR)]	p‐value
1	N1	Copies/ml	45.5 (11.1–145) vs. 719 (76.9–1141)	<0.001
		Copies/copies PMMoV	2.6 × 10−2 (6.5 × 10−3–6 × 10−2) vs. 2.3 × 10−1 (4.1 × 10−2–3.7 × 10−1)	<0.001
	N200	Copies/ml	12.7 (3.1–20.3) vs. 347 (7.8–477)	0.001
		Copies/copies PMMoV	5.3 × 10−3 (1.6 × 10−3–1.3 × 10−2) vs. 8 × 10−2(7.7 × 10−3–1.8 × 10−1)	<0.001
2	N1	Copies/ml	9.9 (5.1–73.9) vs. 167 (39–354)	<0.001
		Copies/copies PMMoV	4.8 × 10−3 (1.7 × 10−3–6.6 × 10−2) vs. 3.7 × 10−2 (1.3 × 10−2–3 × 10−1)	0.005
	N200	Copies/ml	5.2 (0.7–18.5) vs. 36.6 (13.3–220)	<0.001
		Copies/copies PMMoV	3 × 10−3(2.6 × 10−4–1.4 × 10−2) vs. 1.5 × 10−2 (3.3 × 10−3–8.4 × 10−2)	0.007
3A	N1	Copies/ml	20.5 (3.9–47.1) vs. 211 (118–303)	0.033
		Copies/copies PMMoV	1.8 × 10−2 (4.9 × 10−3–7 × 10−2) vs. 1.2 × 10−1 (5.2 × 10−3–2.4 × 10−1)	0.723
	N200	Copies/ml	12.6 (2.7–35.8) vs. 204 (47.8–361)	0.052
		Copies/copies PMMoV	9.5 × 10−3 (2.1 × 10−3–3.5 × 10−2) vs. 1.5 × 10−1(2.1 × 10−3–2.9 × 10−1)	0.723
3B	N1	Copies/ml	10.3 (1.1–22.7) vs. 105 (4.8–447)	0.003
		Copies/copies PMMoV	4.5 × 10−3 (3.1 × 10−4–8.1 × 10−3) vs 6.1 × 10−2 (2.4 × 10−3–1.3 × 10−1)	0.008
	N200	Copies/ml	1.3 (0–7.4) vs. 34.7 (1.1–158)	0.006
		Copies/copies PMMoV	4.2 × 10− 4 (0–3.7 × 10−3) vs. 2.1 × 10−2 (1.9 × 10−4–5.4 × 10−2)	0.014
3C	N1	Copies/ml	3.3 (0−13.5) vs. 77 (15.8−269)	0.003
		Copies/copies PMMoV	2.5 × 10−3 (0–1.1 × 10−2) vs. 5.2 × 10−2 (3.6 × 10−3–5.2 × 10−1)	0.003
	N200	Copies/ml	0.6 (0–5.3) vs. 91.6 (11.3–260)	<0.001
		Copies/copies PMMoV	2.3 × 10−4 (0–3.9 × 10−3) vs. 2.9 × 10−2 (2.2  × 10−3–5.2 × 10−1)	<0.001

Abbreviation: IQR, interquartile range.